Frosth Sara, Karlsson-Lindsjö Oskar, Niazi Adnan, Fernström Lise-Lotte, Hansson Ingrid
Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, P.O. Box 7036, SE-750 07 Uppsala, Sweden.
SLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, P. O. Box 7023, SE-750 07 Uppsala, Sweden.
Pathogens. 2020 May 9;9(5):363. doi: 10.3390/pathogens9050363.
An in-depth analysis was performed on Swedish broiler producers that had delivered chickens with to slaughter over several years, in order to identify possible transmission routes and formulate effective measures to prevent chickens being colonized with Between 2017 and 2019, 626 samples were collected at farm level and was isolated from 133 (21.2%). All and isolated from these samples were whole-genome sequenced, together with isolates from the corresponding cecum samples at slaughter ( = 256). Core genome multi-locus sequence typing (cgMLST) analysis, using schemes consisting of 1140 and 529 genes for and , respectively, revealed that nearby cattle, contaminated drinking water, water ponds, transport crates, and parent flocks were potential reservoirs of A novel feature compared with previous studies is that measures were implemented and tested during the work. These contributed to a nationwide decrease in positive flocks from 15.4% in 2016 to 4.6% in 2019, which is the lowest ever rate in Sweden. To conclude, there are different sources and routes of transmission to chickens from different broiler producers, and individual measures must be taken by each producer to prevent colonization of chickens.
对多年来一直向屠宰场供应鸡的瑞典肉鸡生产商进行了深入分析，以确定可能的传播途径，并制定有效措施防止鸡被[病原体名称]定植。在2017年至2019年期间，在农场层面收集了626份样本，其中133份（21.2%）分离出了[病原体名称]。从这些样本中分离出的所有[病原体名称]都进行了全基因组测序，同时还对屠宰时相应盲肠样本中的分离株（n = 256）进行了测序。核心基因组多位点序列分型（cgMLST）分析分别使用由1140个和529个基因组成的方案对[病原体名称1]和[病原体名称2]进行分析，结果显示附近的牛、受污染的饮用水、水塘、运输箱和种鸡群是[病原体名称]的潜在储存宿主。与以往研究相比，一个新特点是在工作过程中实施并测试了相关措施。这些措施促使全国阳性鸡群的比例从2016年的15.4%降至2019年的4.6%，这是瑞典有史以来的最低比例。总之，不同肉鸡生产商的鸡感染[病原体名称]有不同的来源和途径，每个生产商必须采取个别措施来防止鸡被[病原体名称]定植。
