Chau Dao Thi Minh, Chung Nguyen Thanh, Huong Le Thi, Hung Nguyen Huy, Ogunwande Isiaka A, Dai Do Ngoc, Setzer William N
Institute of Biochemical Technology and Environment, Vinh University, 182 Le Duan, Vinh City 4300, Nghệ An Province, Vietnam.
Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Cau Giay 10072, Hanoi, Vietnam.
Plants (Basel). 2020 May 10;9(5):606. doi: 10.3390/plants9050606.
The Lauraceae is a family rich in aromatic and medicinal plants. Likewise, essential oils derived from members of this family have demonstrated a myriad of biological activities. It is hypothesized that members of the Lauraceae from Vietnam will yield essential oils that may be useful in controlling mosquito populations and treating microbial infections. In this work, the leaf essential oils of eleven species of Lauraceae (, , , , , , , , , , and ) have been obtained by hydrodistillation and the chemical compositions analyzed by gas chromatography - mass spectrometry (GC-MS) and gas chromatography with flame ionization detection (GC-FID). The essential oils were screened for larvicidal activity against , , and , and for antimicrobial activity against , , , , , , and . The leaf essential oil of , rich in ()-β-ocimene (87.6%), showed excellent larvicidal activity against with a 24 h LC of 6.59 μg/mL. The leaf essential oil of , dominated by germacrene D (55.5%) and bicyclogermacrene (11.4%), exhibited remarkable larvicidal activity against (48 h LC = 0.40 μg/mL). leaf essential oil also demonstrated notable antibacterial activity against and with minimum inhibitory concentration (MIC) values of 16 μg/mL, while the leaf essential oil of showed excellent anticandidal with an MIC of 16 μg/mL. Leaf essential oils from the Lauraceae should be considered for utilization as alternative agents for controlling mosquito populations and as antimicrobial agents.
樟科是一个富含芳香植物和药用植物的科。同样，从该科植物中提取的精油已显示出多种生物活性。据推测，越南的樟科植物可能会产生有助于控制蚊虫数量和治疗微生物感染的精油。在这项研究中，通过水蒸馏法获得了11种樟科植物（ 、 、 、 、 、 、 、 、 、 、 ）的叶精油，并采用气相色谱 - 质谱联用仪（GC-MS）和带火焰离子化检测的气相色谱仪（GC-FID）分析了其化学成分。对这些精油进行了针对 、 、 的杀幼虫活性筛选，以及针对 、 、 、 、 、 、 的抗菌活性筛选。富含（）-β-罗勒烯（87.6%）的 的叶精油对 显示出优异的杀幼虫活性，24小时半数致死浓度（LC）为6.59μg/mL。以杜松烯D（55.5%）和双环杜松烯（11.4%）为主的 的叶精油对 表现出显著的杀幼虫活性（48小时LC = 0.40μg/mL）。 的叶精油对 和 也显示出显著的抗菌活性，最低抑菌浓度（MIC）值为16μg/mL，而 的叶精油对白色念珠菌表现出优异的抗真菌活性，MIC为16μg/mL。樟科植物的叶精油应被考虑用作控制蚊虫数量的替代剂和抗菌剂。
