Silva Rafael Alves da, Antonieti Flávia Maria Pinto Monteiro, Röder Denise Von Dolinger de Brito, Pedroso Reginaldo Dos Santos
Post-Graduation Program in Health Sciences, Federal University of Uberlândia, Uberlândia 38400-902, MG, Brazil.
Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 38400-902, MG, Brazil.
Pharmaceutics. 2021 Oct 15;13(10):1700. doi: 10.3390/pharmaceutics13101700.
is a common agent of infection in humans, which has a wide distribution and is a colonizer fungus of the body, occasionally assuming the role of a pathogen. The type of treatment depends on the site of infection and the clinical condition of the patient. Superficial infections, such as mucosal infections, can be treated with topical medications. So-called alternative therapies have rarely been studied, although the literature records the effectiveness of some treatments, especially as complementary therapy. The aims of this review were to analyze evidence of the anti- inhibitory activity of essential oils of the , , , and species; in addition to addressing the chemical composition, probable mechanisms of antifungal action and studies of toxicity, cytotoxicity, and genotoxicity were included. The literature from Medline/PubMed, Science Direct, Scopus, Web of Science, and the Brazilian database Periodic Capes was reviewed. Thirty-eight articles were selected, which included two articles on spp., seven on spp., thirteen articles on spp., and twenty-one articles on spp. In conclusion, this study showed in vitro evidence for the use of essential oils of the plant species evaluated for the treatment of infections caused by different species.
是人类常见的感染源，分布广泛，是人体的定植真菌，偶尔扮演病原体的角色。治疗类型取决于感染部位和患者的临床状况。浅表感染，如黏膜感染，可用局部用药治疗。尽管文献记载了一些治疗方法的有效性，尤其是作为辅助疗法，但所谓的替代疗法很少被研究。本综述的目的是分析 、 、 和 物种精油的抗抑制活性证据；此外，还包括化学成分、抗真菌作用的可能机制以及毒性、细胞毒性和遗传毒性研究。对来自Medline/PubMed、Science Direct、Scopus、Web of Science和巴西数据库Periodic Capes的文献进行了综述。共筛选出38篇文章，其中关于 属的文章2篇，关于 属的文章7篇，关于 属的文章13篇，关于 属的文章21篇。总之，本研究显示了体外证据，支持使用所评估植物物种的精油治疗由不同 物种引起的感染。
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