Gharbiya Magda, Albanese Giuseppe Maria, Plateroti Andrea Maria, Marcelli Michela, Marenco Marco, Lambiase Alessandro
Ophthalmology Unit, Department of Sense Organs, Sapienza University of Rome, Umberto I University Hospital, 00161 Rome, Italy.
J Clin Med. 2020 May 10;9(5):1411. doi: 10.3390/jcm9051411.
(1) Background: We evaluated macular ganglion cell layer-inner plexiform layer (GCL-IPL) thickness in patients with primary macula-off rhegmatogenous retinal detachment (RRD) treated with scleral buckling (SB) or pars plana vitrectomy (PPV) using spectral domain optical coherence tomography (SD-OCT). (2) Methods: In this retrospective, observational study, we reviewed the medical records of patients undergoing SB or PPV surgery for macula-off RRD. SD-OCT was performed at three and 12 months after surgery. The central and parafoveal GCL-IPL thicknesses in treated eyes were compared with those of healthy fellow eyes. OCT measurements between the SB and PPV group were also compared using the analysis of covariance. (3) Results: Seventy-one eyes of 71 patients with a mean age of 61.2 ± 11.7 years were included. The parafoveal GCL-IPL thickness of the PPV group was significantly reduced, with respect to fellow eyes, at three and 12 months ( < 0.01). After adjusting for age, axial length, spherical equivalent, RD extent, preoperative intraretinal cysts, duration of symptoms and postoperative IOP, the parafoveal GCL-IPL thickness in the PPV group was significantly reduced with respect to the SB group, both at three and 12 months (F = 11.45, = 0.001 and F = 12.37, = 0.001, respectively). (4) Conclusions: In conclusion, the GCL-IPL is reduced in thickness in eyes with macula-off RRD treated with vitrectomy and is significantly thinner compared to eyes undergoing scleral buckling surgery.
（1）背景：我们使用光谱域光学相干断层扫描（SD-OCT）评估了巩膜扣带术（SB）或玻璃体切割术（PPV）治疗原发性黄斑脱离性孔源性视网膜脱离（RRD）患者的黄斑神经节细胞层-内丛状层（GCL-IPL）厚度。（2）方法：在这项回顾性观察研究中，我们回顾了接受SB或PPV手术治疗黄斑脱离性RRD患者的病历。术后3个月和12个月进行SD-OCT检查。将治疗眼的中央和旁中心凹GCL-IPL厚度与健康对侧眼进行比较。还使用协方差分析比较了SB组和PPV组之间的OCT测量结果。（3）结果：纳入71例患者的71只眼，平均年龄61.2±11.7岁。PPV组旁中心凹GCL-IPL厚度在术后3个月和12个月相对于对侧眼显著降低（<0.01）。在调整年龄、眼轴长度、等效球镜度、视网膜脱离范围、术前视网膜内囊肿、症状持续时间和术后眼压后，PPV组旁中心凹GCL-IPL厚度在术后3个月和12个月相对于SB组均显著降低（F = 11.45，P = 0.001和F = 12.37，P = 0.001）。（4）结论：总之，玻璃体切割术治疗黄斑脱离性RRD的患眼GCL-IPL厚度降低，与巩膜扣带术治疗的患眼相比明显更薄。
