Sato Tatsuhiko, Wakabayashi Taku, Shiraki Nobuhiko, Sakaguchi Hirokazu
Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1737-1742. doi: 10.1007/s00417-017-3716-8. Epub 2017 Jun 21.
To investigate retinal thickness in the central and parafoveal subfields, including segmented analysis of the inner and outer retinal layers, after vitrectomy for macula-off rhegmatogenous retinal detachment (RRD) repair.
Twenty-four eyes of 24 patients who underwent primary vitrectomy for macula-off RRD repair were enrolled in this study. Spectral-domain optical coherence tomography examination and best-corrected visual acuity (BCVA) measurements were performed at 1, 3, and 6 months after vitrectomy.
At 1, 3, and 6 months after vitrectomy, retinal thickness in the temporal parafoveal subfield was more significantly (P = 0.004, 0.001, and 0.003, respectively) correlated with BCVA than the central subfield (P = 0.014, 0.001, and 0.022, respectively). Segmented analysis showed significant correlations between the retinal thickness of both the outer layer (P = 0.018, 0.030, and 0.018, respectively) and the inner layer (P = 0.003, 0.002, and 0.001, respectively) in the temporal parafoveal subfield and BCVA at every time point after vitrectomy.
These results suggest that retinal thickness in the temporal parafoveal subfield may most closely reflect postoperative BCVA after macula-off RRD repair.
研究黄斑脱离性孔源性视网膜脱离（RRD）修复玻璃体切除术后中央和旁中心凹子区域的视网膜厚度，包括视网膜内、外层的分段分析。
本研究纳入24例接受黄斑脱离性RRD修复一期玻璃体切除术的患者的24只眼。在玻璃体切除术后1、3和6个月进行光谱域光学相干断层扫描检查和最佳矫正视力（BCVA）测量。
玻璃体切除术后1、3和6个月，颞侧旁中心凹子区域的视网膜厚度与BCVA的相关性比中央子区域更显著（分别为P = 0.004、0.001和0.003）（分别为P = 0.014、0.001和0.022）。分段分析显示玻璃体切除术后每个时间点颞侧旁中心凹子区域外层（分别为P = 0.018、0.030和0.018）和内层（分别为P = 0.003、0.002和0.001）的视网膜厚度与BCVA之间均存在显著相关性。
这些结果表明，颞侧旁中心凹子区域的视网膜厚度可能最能密切反映黄斑脱离性RRD修复术后的BCVA。
