Bočková M, Veselý P, Synek S, Hanák L, Beneš P
Cesk Slov Oftalmol. 2019 Winter;75(5):260-264. doi: 10.31348/2019/5/3.
This work deals with sensitivity and specificity in spectral OCT in detection of early glaucoma. Our goal was to evaluate data from RNFL analysis and compare them with resulted diagnosis of glaucoma neuropathy based on visual field changes. This retrospective study contains 31 subjects who undergone OCT examination in our department between years 2008 and 2017. Test statistic showed RNFL OCT sensitivity 63.64 % and specificity 90 %. Test ROC (receiver operating characteristic curve) showed AUC (area under curve) 0.734, which was statistically significant (p = 0.0097). We found that spectral OCT SLO with RNFL analysis is useful and effective instrument in analysis of glaucoma.
这项工作涉及光谱光学相干断层扫描(OCT)在早期青光眼检测中的敏感性和特异性。我们的目标是评估视网膜神经纤维层(RNFL)分析的数据,并将其与基于视野变化得出的青光眼神经病变诊断结果进行比较。这项回顾性研究纳入了2008年至2017年间在我们科室接受OCT检查的31名受试者。检验统计显示RNFL OCT的敏感性为63.64%,特异性为90%。检验的ROC(受试者工作特征曲线)显示曲线下面积(AUC)为0.734,具有统计学意义(p = 0.0097)。我们发现,结合RNFL分析的光谱OCT扫描激光眼底镜(SLO)是分析青光眼的有用且有效的工具。