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高血压与种族/民族。

Hypertension and race/ethnicity.

机构信息

Tulane University School of Medicine, New Orleans, LA, USA.

出版信息

Curr Opin Cardiol. 2020 Jul;35(4):342-350. doi: 10.1097/HCO.0000000000000742.

DOI:10.1097/HCO.0000000000000742
PMID:32398604
Abstract

PURPOSE OF REVIEW

United States racial/ethnic minorities may experience disproportionate hypertension (HTN) morbidity and mortality. This review discusses recent literature regarding the differential impact of HTN, especially among African Americans and Hispanics.

RECENT FINDINGS

Although disparities in HTN prevalence, control, and outcomes persist in racial/ethnic minorities relative to non-Hispanic Whites, racial/ethnic minorities are frequently underrepresented in genetic and clinical studies. Genomics have improved our understanding of HTN, but with no clinically useful application, the role of social determinants of health in HTN disparities is increasingly recognized. Team-based approaches with targeted, multilevel interventions may overcome barriers that uniquely impact racial/ethnic minorities.

SUMMARY

Despite extensive epidemiological research, racial/ethnic minorities remain at higher risk HTN-related morbidity and mortality. Translational efforts may address the differential impact of HTN in racial/ethnic minorities. This review highlights recent research and concepts related to HTN and race/ethnicity.

摘要

目的综述

美国的少数族裔可能面临不成比例的高血压(HTN)发病率和死亡率。本文综述了近期有关 HTN 差异影响的文献,特别是针对非裔美国人和西班牙裔。

最近的发现

尽管与非西班牙裔白人相比,少数族裔的 HTN 患病率、控制率和结局仍存在差异,但少数族裔在遗传和临床研究中经常代表性不足。基因组学提高了我们对 HTN 的认识,但由于没有临床应用,健康的社会决定因素在 HTN 差异中的作用越来越受到重视。以团队为基础的方法,采取有针对性的多层次干预措施,可能克服对少数族裔有独特影响的障碍。

总结

尽管进行了广泛的流行病学研究,但少数族裔仍然面临更高的 HTN 相关发病率和死亡率风险。转化研究可能会解决少数族裔中 HTN 的差异影响。本文综述了与 HTN 和种族/民族相关的最新研究和概念。

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