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抗微生物药物耐药性是一个全球性问题——英国视角。

Antimicrobial resistance is a global problem - a UK perspective.

作者信息

Hu Xiao-Yang, Logue Martin, Robinson Nicola

机构信息

School of Primary Care, Population Sciences and Medical Education, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, SO16 5ST, United Kingdom.

Emeritus Professor of Traditional Chinese Medicine and Integrated Health, School of Health and Social Care, London South Bank University, London, SE1 0AA, United Kingdom.

出版信息

Eur J Integr Med. 2020 Jun;36:101136. doi: 10.1016/j.eujim.2020.101136. Epub 2020 May 12.

Abstract

Increasingly we are reaching a situation where current antimicrobial medicines are no longer effective for common infections, and antimicrobial resistance (AMR) is now a global public health crisis. The reliance on antimicrobials such as antibiotics has become a major issue for both medicine and agriculture, particularly given the slow development of new medicines and pharmaceutical industry investment. The UK government has been working with other international bodies in the search for solutions to the many challenges AMR poses. Herbal medicines may provide a useful modality in the fight against AMR and can work solely or in tandem with current antimicrobial approaches. Recommendations for herbal medicine use during the COVID-19 viral pandemic have featured in Chinese national guidelines and policies, but UK strategies have no such guidance on herbal treatment for any infectious disease. More research is urgently needed to explore the biological plausibility and safety of herbal medicines to manage AMR. AMR is universal, affecting anyone and everyone, at any age and in any country. Investigating how such approaches can be integrated into western medicine will be important to elucidate.

摘要

目前,我们日益面临这样一种局面:现有的抗菌药物对常见感染已不再有效,抗菌药物耐药性(AMR)如今已成为全球公共卫生危机。对诸如抗生素等抗菌药物的依赖已成为医学和农业领域的一个重大问题,尤其是考虑到新药研发进展缓慢以及制药行业的投资情况。英国政府一直在与其他国际机构合作,以寻求应对AMR带来的诸多挑战的解决方案。草药可能在对抗AMR方面提供一种有用的方式,并且可以单独发挥作用,或者与当前的抗菌方法协同发挥作用。中国的国家指南和政策中提及了在COVID - 19病毒大流行期间使用草药的建议,但英国的策略中没有针对任何传染病的草药治疗方面的此类指导。迫切需要开展更多研究,以探索草药用于应对AMR的生物学合理性和安全性。AMR具有普遍性,会影响任何年龄、任何国家的任何人。研究如何将此类方法融入西医将对阐明相关问题具有重要意义。

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