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金诱导细胞因子(GOLDIC)注射疗法治疗足底筋膜炎患者:一例报告

Gold-Induced Cytokine (GOLDIC) Injection Therapy in Patient with Plantar Fasciosis: A Case Report.

作者信息

Melo Sergio Nicolas Sardon, Ezekwesili Agnes, Yurdi Nagib A, Murrell William D, Maffulli Nicola

机构信息

Emirates Integra Medical and Emirates Integra Medical and Surgery and Surgery Centre, Department Orthopaedic Sports Medicine, Dubai Healthcare City, Dubai, United Arab Emirates.

2University of North Carolina, Chapel Hill, NC USA.

出版信息

Indian J Orthop. 2020 Mar 26;54(3):348-351. doi: 10.1007/s43465-020-00089-4. eCollection 2020 May.

Abstract

A novel technique of cultivating autologous blood with gold particles; then separating the gold particles and cells from the serum and injecting the conditioned serum into affected plantar fascia. A first-time report of the safety and efficacy in treatment of recalcitrant plantar fasciosis in an Olympic equestrian. A single patient with clinical signs, symptoms and ultrasound evidence of plantar fasciosis was treated with four intra-ligamentous GOLDIC injection therapy. The Olympic jumper was evaluated by Visual Analog Scale (VAS), Foot and Ankle Disability Index (FADI), and Global Rating of Change (GRoC) score(s) before injection and at 6-month follow-up. VAS, FADI, and GRoC scores showed substantial and marked improvement clinically. The subject was able to return to sport without limitations after 8 weeks. The initial result demonstrates that the treatment regimen is safe, and efficacious. The subject demonstrated reduction of pain, and improved function that allowed return to high level competition.

摘要

一种用金颗粒培养自体血液的新技术;然后从血清中分离出金颗粒和细胞,并将条件血清注入受影响的足底筋膜。首次报道在一名奥运会马术运动员中治疗顽固性足底筋膜炎的安全性和有效性。一名有足底筋膜炎临床体征、症状和超声证据的患者接受了四次韧带内GOLDIC注射治疗。在注射前和6个月随访时,通过视觉模拟量表(VAS)、足踝残疾指数(FADI)和总体变化评分(GRoC)对该奥运会跳远运动员进行评估。VAS、FADI和GRoC评分在临床上显示出显著且明显的改善。该受试者在8周后能够不受限制地恢复运动。初步结果表明该治疗方案安全且有效。该受试者疼痛减轻,功能改善,能够恢复高水平比赛。

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