CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Braz J Psychiatry. 2021 Feb 1;43(1):29-34. doi: 10.1590/1516-4446-2020-0900. eCollection 2020.
The purpose of this study was to investigate the lifetime suicide attempt rate, clinical characteristics and cognitive function of Chinese patients with chronic schizophrenia who had attempted suicide.
We collected data from 908 schizophrenia inpatients about suicide attempts through interviews with the patients and their families, as well as through medical records. All patients were assessed with the Positive and Negative Syndrome Scale, the Rating Scale for Extrapyramidal Side Effects, the Abnormal Involuntary Movement Scale, and the Repeated Battery for the Assessment of Neuropsychological Status.
Of this sample, 97 (10.68%) had attempted suicide. Patients who had attempted suicide were younger, had longer illness duration, and more severe general psychopathology and depressive symptoms than those who had not. Logistic regression analysis confirmed that suicide attempts were correlated with age, smoking, and depression. No cognitive performance differences were observed between patients who had and had not attempted suicide.
In China, patients with chronic schizophrenia may have a higher prevalence of lifetime suicide attempts than the general population. Some demographic and clinical variables were related to suicide attempts in patients with chronic schizophrenia.
本研究旨在调查中国慢性精神分裂症患者自杀未遂的终生自杀未遂率、临床特征和认知功能。
我们通过对患者及其家属的访谈以及病历，收集了 908 名住院精神分裂症患者的自杀尝试数据。所有患者均接受阳性和阴性症状量表、锥体外系副作用评定量表、异常不自主运动量表和重复神经心理状态评估电池的评估。
在该样本中，有 97 人（10.68%）曾试图自杀。与未自杀的患者相比，自杀未遂的患者年龄较小，病程较长，一般精神病和抑郁症状更严重。Logistic 回归分析证实，自杀未遂与年龄、吸烟和抑郁有关。在是否尝试过自杀的患者之间，未观察到认知表现的差异。
在中国，慢性精神分裂症患者的终生自杀未遂率可能高于一般人群。一些人口统计学和临床变量与慢性精神分裂症患者的自杀未遂有关。
