四株卡介苗疫苗的全基因组序列测定。
Newly sequenced genomes of four Bacillus Calmette Guerin vaccines.
机构信息
Departamento de Microbiologia Médica, Laboratório de Micobactérias, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Instituto Nacional de Enfermedades Infecciosas, Buenos Aires, Argentina.
出版信息
Mem Inst Oswaldo Cruz. 2020;115:e190401. doi: 10.1590/0074-02760190401. Epub 2020 May 11.
Abstract
Bacillus Calmette Guerin (BCG) vaccines comprise a family of related strains. Whole genome sequencing has allowed the better characterisation of the differences between many of the BCG vaccines. As sequencing technologies improve, updating of publicly available sequence data becomes common practice. We hereby announce the draft genome of four commonly used BCG vaccines in Brazil, Argentina and Venezuela.
摘要
卡介苗（BCG）疫苗由一系列相关菌株组成。全基因组测序技术使人们能够更好地描述许多 BCG 疫苗之间的差异。随着测序技术的不断改进，更新公开可用的序列数据已成为常见做法。在此，我们公布了巴西、阿根廷和委内瑞拉常用的四种 BCG 疫苗的草图基因组。
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