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1991-2015 年期间一般人群的疼痛发生率及 10 年预测:多洲年龄-时期-队列分析的结果。

Pain rates in general population for the period 1991-2015 and 10-years prediction: results from a multi-continent age-period-cohort analysis.

机构信息

Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.

Parc Sanitari Sant Joan de Déu, Fundacion Sant Joan de Deu, Barcelona, Spain.

出版信息

J Headache Pain. 2020 May 13;21(1):52. doi: 10.1186/s10194-020-01108-3.

DOI:10.1186/s10194-020-01108-3
PMID:32404046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7218619/
Abstract

BACKGROUND

Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The aims of this study are to evaluate the temporal variations of pain rates among general populations for the period 1991-2015 and to project 10-year pain rates.

METHODS

We used the harmonized dataset of ATHLOS project, which included 660,028 valid observations in the period 1990-2015 and we applied Bayesian age-period-cohort modeling to perform projections up to 2025. The harmonized Pain variable covers the content "self-reported pain experienced at the time of the interview", with a dichotomous (yes or no) modality.

RESULTS

Pain rates were higher among females, older subjects, in recent periods, and among observations referred to cohorts of subjects born between the 20s and the 60s. The 10-year projections indicate a noteworthy increase in pain rates in both genders and particularly among subjects aged 66 or over, for whom a 10-20% increase in pain rate is foreseen; among females only, a 10-15% increase in pain rates is foreseen for those aged 36-50.

CONCLUSIONS

Projected increase in pain rates will require specific interventions by health and welfare systems, as pain is responsible for limited quality of subjective well-being, reduced employment rates and hampered work performance. Worksite and lifestyle interventions will therefore be needed to limit the impact of projected higher pain rates.

摘要

背景

疼痛是一种常见症状,常与神经和肌肉骨骼疾病有关,尤其在女性和老年人中更为常见。本研究旨在评估 1991-2015 年期间一般人群中疼痛发生率的时间变化,并预测 10 年的疼痛发生率。

方法

我们使用了 ATHLOS 项目的协调数据集,该数据集包括 1990-2015 年期间的 660028 个有效观察值,并应用贝叶斯年龄-时期-队列模型进行了 2025 年的预测。协调的疼痛变量涵盖了“在访谈时自我报告的疼痛经历”的内容,采用二分法(是或否)模式。

结果

女性、年龄较大的受试者、近期和出生于 20 世纪 20 年代至 60 年代的队列的受试者中,疼痛发生率较高。10 年预测表明,两性的疼痛发生率都有显著增加,特别是 66 岁及以上的受试者,预计疼痛发生率将增加 10-20%;仅在女性中,预计 36-50 岁的女性疼痛发生率将增加 10-15%。

结论

疼痛发生率的预计增加将需要卫生和福利系统采取具体干预措施,因为疼痛会导致主观幸福感受限、就业率降低和工作表现受阻。因此,需要进行工作场所和生活方式干预,以限制预计更高的疼痛发生率的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/531c043b2846/10194_2020_1108_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/15a8e288f1aa/10194_2020_1108_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/028359eb2d2d/10194_2020_1108_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/722648067dd1/10194_2020_1108_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/531c043b2846/10194_2020_1108_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/15a8e288f1aa/10194_2020_1108_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/028359eb2d2d/10194_2020_1108_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/83be9ae43be7/10194_2020_1108_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/722648067dd1/10194_2020_1108_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed96/7218619/531c043b2846/10194_2020_1108_Fig5_HTML.jpg

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