Department of Neurosurgery, Kantonsspital St. Gallen, Rorschacher Strasse 95, 9001, St. Gallen, Switzerland.
Neuro and Spine Center, Hirslanden Clinic St. Anna, Lucerne, Switzerland.
Acta Neurochir (Wien). 2020 Sep;162(9):2061-2068. doi: 10.1007/s00701-020-04377-8. Epub 2020 May 13.
The worldwide spread of smartphone usage enables new possibilities for longitudinal monitoring of objective functional impairment (OFI) in patients undergoing surgery for lumbar degenerative disc disease (DDD).
Three patients, undergoing elective surgery for lumbar DDD, self-assessed OFI using a recently validated 6-min walking test (6WT) smartphone application. Results are presented as raw 6-min walking distance (6WD) as well as in reference to age- and sex-specific healthy population reference values using standardized z-scores (number of standard deviations). In parallel, patient-reported outcome measures (PROMs), including numeric rating scale (NRS) leg-pain and Core Outcome Measures Index (COMI) were obtained before (pre) and 6 weeks (6 W) as well as 3 months (3 M) after surgery. Descriptive analyses were used to compare PROMs with repeated 6WT measurements over time. The feasibility and benefits of the longitudinal OFI measurements using the 6WT app are discussed.
One patient presented a favorable outcome, reflected by a clinically meaningful improvement in PROMs. Correspondingly, the 6WT distance gradually improved above the normal population values ((pre 399 m (z-score - 1.96) vs. 6 W 494 m (- 0.85) vs. 3 M 557 m (- 0.1)). One patient experienced initial improvement at 6 W, followed by a decline in 6WD at 3 M which promoted further interventions with subsequent recovery ((358 m (z-score - 3.29) vs 440 m (- 2.2) vs 431 m (- 2.32) vs 471 m (- 1.78)). The last patient showed a lack of improvement in PROMs as well as in OFI (360 m (z-score 0.0) vs 401 m (0.30) vs 345 m (- 0.11)) resulting in secondary surgery.
The longitudinal assessment of OFI using the 6WT app was feasible and provided the physician with a detailed history of patients' postoperative walking capacity complementing commonly used PROMs.
智能手机在全球范围内的普及为腰椎退行性疾病(DDD)患者术后的客观功能障碍(OFI)进行纵向监测提供了新的可能性。
3 名接受择期腰椎 DDD 手术的患者使用最近验证的 6 分钟步行测试(6WT)智能手机应用程序自我评估 OFI。结果以未经调整的 6 分钟步行距离(6WD)表示,并以年龄和性别特异性健康人群参考值为参照,使用标准化 z 分数(标准差的数量)表示。同时,患者报告的结果测量(PROM),包括数字评分量表(NRS)腿部疼痛和核心结局测量指数(COMI),在术前(术前)、术后 6 周(6W)和 3 个月(3M)进行了评估。使用重复 6WT 测量来比较随时间推移的 PROM,进行描述性分析。讨论了使用 6WT 应用程序进行纵向 OFI 测量的可行性和益处。
一名患者的预后较好,PROM 有明显的临床改善。相应地,6WT 距离逐渐改善至高于正常人群值((术前 399m(z 分数-1.96)vs. 6W 494m(-0.85)vs. 3M 557m(-0.1))。一名患者在 6W 时最初有所改善,随后在 3M 时 6WD 下降,这促使进行了进一步的干预,随后恢复((358m(z 分数-3.29)vs. 440m(-2.2)vs. 431m(-2.32)vs. 471m(-1.78))。最后一名患者的 PROM 和 OFI 均无改善(360m(z 分数 0.0)vs. 401m(0.30)vs. 345m(-0.11)),导致进行了二次手术。
使用 6WT 应用程序对 OFI 进行纵向评估是可行的,为医生提供了患者术后步行能力的详细病史,补充了常用的 PROM。