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接受硬膜外类固醇注射患者基于智能手机的客观功能障碍自我评估(6分钟步行试验)

Smartphone-Based Self-Assessment of Objective Functional Impairment (6-Minute Walking Test) in Patients Undergoing Epidural Steroid Injection.

作者信息

Zeitlberger Anna Maria, Sosnova Marketa, Ziga Michal, Steinsiepe Valentin, Gautschi Oliver P, Stienen Martin N, Maldaner Nicolai

机构信息

Department of Neurosurgery, Kantonsspital St. Gallen, St. Gallen, Switzerland.

Neuro- and Spine Center, Hirslanden Clinic St. Anna, Lucerne, Switzerland.

出版信息

Neurospine. 2020 Mar;17(1):136-142. doi: 10.14245/ns.2040022.011. Epub 2020 Mar 31.

Abstract

Epidural steroid injection (ESI) represents a popular treatment option in patients with lumbar degenerative disc disease (DDD). The main objective of the article was to determine whether the 6-minute walking test (6WT) could assist in the discrimination between ESI responders and nonresponders. We used a validated 6WT smartphone application to assess self-measured objective functional impairment (OFI) in 3 patients with DDD undergoing ESI. Patient-reported outcome measures (PROMs), including the Core Outcome Measures Index and the Oswestry Disability Index, were obtained at baseline and at the 3-, 7-, and 28-day follow-up. Descriptive analyses were used to compare PROMs with OFI over time. Two patients responded well to the ESI, illustrated by clinically meaningful improvements in PROMs. This improvement was accompanied by a substantial increase in the 6WT distance (case I: 358 m vs. 517 m and case II: 296 m vs. 625 m). One patient reported only moderate improvement in leg pain and conflicting results in the other PROMs. The 6WT demonstrated a persistent OFI (487 m vs. 488 m). This patient was considered a nonresponder and underwent surgical treatment. This case series illustrates the feasibility of the smartphone-based 6WT as a tool to assess OFI in patients undergoing ESI for lumbar DDD.

摘要

硬膜外类固醇注射(ESI)是腰椎退行性椎间盘疾病(DDD)患者常用的治疗选择。本文的主要目的是确定6分钟步行试验(6WT)是否有助于区分ESI治疗的反应者和无反应者。我们使用一款经过验证的6WT智能手机应用程序,对3例接受ESI治疗的DDD患者的自我测量客观功能障碍(OFI)进行评估。在基线以及随访的第3天、第7天和第28天,获取患者报告的结局指标(PROMs),包括核心结局指标指数和Oswestry功能障碍指数。采用描述性分析比较不同时间点的PROMs和OFI。2例患者对ESI反应良好,PROMs有临床意义的改善。这种改善伴随着6WT步行距离的大幅增加(病例I:358米对517米,病例II:296米对625米)。1例患者仅报告腿痛有中度改善,其他PROMs结果相互矛盾。6WT显示OFI持续存在(487米对488米)。该患者被视为无反应者并接受了手术治疗。这个病例系列说明了基于智能手机的6WT作为评估接受ESI治疗腰椎DDD患者OFI工具的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d859/7136089/a66916a01646/ns-2040022-011f1.jpg

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