Carnevale P, Robert V, Boudin C, Halna J M, Pazart L, Gazin P, Richard A, Mouchet J
Centre Muraz, Burkina Faso.
Bull Soc Pathol Exot Filiales. 1988;81(5):832-46.
An experimental trial of malaria control was carried out in the village of Karangasso in the south-west Burkina Faso. It was based on the use by the whole population of deltamethrin impregnated bed nets at 25 mg/m2. During the first year pretreatment data on entomology, parasitology and pathological incidence of malaria were collected in the whole village. During the second year a quarter of the village with a population of 1,200 was chosen for the experiment and impregnated bed nets were given to everybody while the other quarter of the same population size was kept as a control area. Malaria transmission was reduced by 82% due to the decrease of both vector populations and sporozoitic indexes. It should be pointed out that this reduction in transmission was evaluated on non-protected catchers and consequently was underestimated for the villagers sleeping under nets. Parasitic index remained about the same but the mean parasitic load decreased significantly. Pathological incidence, based on the number of clinical malaria cases confirmed by blood examination, decreased by 59%. This trial shows that mass use of deltamethrin impregnated bed nets should be considered as a valuable tool for malaria control. The purchase of bed net is expensive but could be reduced sharply. The cost of the impregnation is very low regarding the residual effect which remains one year. The acceptance by the population was good.
在布基纳法索西南部的卡兰加索村开展了一项疟疾控制实验性试验。该试验基于全体村民使用每平方米含25毫克溴氰菊酯的浸药蚊帐。第一年,收集了全村疟疾的昆虫学、寄生虫学及病理发病率的预处理数据。第二年,从全村1200人中选取四分之一进行实验,给每个人发放浸药蚊帐,而将相同人口规模的另外四分之一作为对照区域。由于病媒种群和子孢子指数均下降,疟疾传播减少了82%。应当指出的是,这种传播减少是在未受保护的捕捉者身上评估的,因此对于睡在蚊帐下的村民来说被低估了。寄生虫指数基本保持不变,但平均寄生虫负荷显著下降。基于血液检查确诊的临床疟疾病例数量的病理发病率下降了59%。该试验表明,大规模使用溴氰菊酯浸药蚊帐应被视为控制疟疾的一项有价值工具。蚊帐采购成本高昂,但可大幅降低。就持续一年的残留效果而言,浸药成本非常低。民众对此接受度良好。