Karch S, Garin B, Asidi N, Manzambi Z, Salaun J J, Mouchet J
Service d'Entomologie Médicale, I.N.R.B., Kinshasa, Zaïre.
Ann Soc Belg Med Trop. 1993 Mar;73(1):37-53.
On the Bateké plateau 60 km east of Kinshasa, Zaïre, where malaria is stable, three villages have been selected for a trial of malaria control using bednets impregnated with deltamethrin at 25 mg per square meter from February to November 1991. One village (3,000 inhabitants) has been provided 800 impregnated bednets and an other one (2,900 inhabitants) kept 800 non impregnated bednets. The third village (900 inhabitants) served as a control and has remained without nets. Anopheles gambiae was the main and nearly exclusive vector of malaria. Its biting density was reduced by 94% in the village protected by impregnated bednets and the inoculation rate dropped from 182 infective bites/man/year to 3.7 a decrease of 98%. The longevity of the vector expressed by its expectation of life decreased from 11.02 days to 3.64 days. In the village where inhabitants were protected by non impregnated nets, as well as in the control, the entomological indexes did not change. In the village protected with impregnated nets the malaria prevalence decreased by 50%, five months after the beginning of the experiment. The high parasitemia, above 10,000 and 20,000 parasites per mm3 decreased by 77% and 83% in the 0-7 year age group and by 67% and 65% in the 8-14 year group in the protected village. These high parasitemias are good markers of the clinical malaria risk. The experiment can be considered as very satisfactory on the point of view of public health.
在扎伊尔金沙萨以东60公里处的巴特克高原,那里疟疾流行情况稳定,1991年2月至11月期间,选择了三个村庄进行使用每平方米含25毫克溴氰菊酯的蚊帐控制疟疾的试验。一个村庄(3000名居民)获得了800顶浸药蚊帐,另一个村庄(2900名居民)保留了800顶未浸药蚊帐。第三个村庄(900名居民)作为对照,未使用蚊帐。冈比亚按蚊是疟疾的主要且几乎唯一的传播媒介。在使用浸药蚊帐保护的村庄,其叮咬密度降低了94%,接种率从182次感染性叮咬/人/年降至3.7次,降幅为98%。以预期寿命表示的媒介寿命从11.02天降至3.64天。在居民使用未浸药蚊帐保护的村庄以及对照村庄,昆虫学指标没有变化。在使用浸药蚊帐保护的村庄,实验开始五个月后,疟疾患病率下降了50%。在受保护村庄,0至7岁年龄组每立方毫米高于10000和20000个疟原虫的高疟原虫血症分别下降了77%和83%,8至14岁年龄组分别下降了67%和65%。这些高疟原虫血症是临床疟疾风险的良好指标。从公共卫生角度来看,该实验可被视为非常令人满意。