The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Adimab, Lebanon, NH 03766, USA.
Cell Host Microbe. 2020 May 13;27(5):695-698. doi: 10.1016/j.chom.2020.04.022.
As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term "rational vaccine design." We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and influenza, as well as coronaviruses.
当科学家们考虑 SARS-CoV-2 疫苗设计时，我们讨论了可能遇到的问题，并通过我们所谓的“理性疫苗设计”来讨论如何解决这些问题。我们进一步讨论了泛冠状病毒疫苗的方法。我们借鉴了最近对包括 HIV 和流感在内的几种病毒以及冠状病毒的研究经验。
