Rhinology and Skull Base Research Group, Baton Rouge General Medical Center, Baton Rouge, Louisiana.
Department of Otorhinolaryngology, Cairo University, Cairo, Egypt.
Am J Rhinol Allergy. 2020 Jul;34(4):451-455. doi: 10.1177/1945892420927178. Epub 2020 May 14.
SARS-CoV-2 has been identified as the pathogen causing the outbreak of Coronavirus Disease 2019 (COVID-19) that started in Wuhan, China, in December 2019. SARS-CoV-2 has human-to-human transmission ability and universally contagious to all populations. The main transmission patterns are respiratory droplets transmission and contact transmission. The purpose of this study is to propose a protocol that may be used as a guide to reduce the incidence of COVID-19 infections among otolaryngology care teams.
A prospective cohort study was conducted to show the efficacy of our protocol to prevent transmission to health-care providers from March 11, 2020 through April 14, 2020. The protocol consisted of a series of protective measures that we applied to all health-care providers, then testing of our providers for COVID-19 using reverse transcription polymerase chain reaction along with immunoglobulin M (IgM) and immunoglobulin G (IgG) testing at the end of the study period to ensure effectiveness.
Our protocol resulted in zero transmissions to our health-care providers during the duration of the initial study. We were involved in greater than 150 sinonasal, skull base, open airway, and endoscopy procedures during this study. At the conclusion of the initial 5 weeks, we had no health-care providers test positive for SARS-CoV-2.
According to our proposed protocol, we were able to provide care for all patients in clinic, hospital, emergent, intensive, and surgical settings with no transmission of SARS-CoV-2 by symptomatology and post evaluation testing.
SARS-CoV-2 已被确定为导致 2019 年冠状病毒病(COVID-19)爆发的病原体,该疫情于 2019 年 12 月在中国武汉开始。SARS-CoV-2 具有人际传播能力,普遍对所有人群具有传染性。主要传播方式为呼吸道飞沫传播和接触传播。本研究旨在提出一项方案,以作为减少耳鼻喉科医护人员 COVID-19 感染发病率的指南。
前瞻性队列研究显示,我们的方案可预防 COVID-19 从 2020 年 3 月 11 日至 2020 年 4 月 14 日期间在医护人员中传播。该方案包括一系列保护措施,我们将其应用于所有医护人员,然后在研究结束时使用逆转录聚合酶链反应(RT-PCR)对我们的医护人员进行 COVID-19 检测,以及免疫球蛋白 M(IgM)和免疫球蛋白 G(IgG)检测,以确保有效性。
在最初研究期间,我们的方案使我们的医护人员零传播 COVID-19。在此期间,我们参与了超过 150 例鼻-鼻窦、颅底、开放气道和内窥镜手术。在最初的 5 周结束时,我们没有医护人员检测出 SARS-CoV-2 呈阳性。
根据我们提出的方案,我们能够在诊所、医院、急诊、重症监护和手术环境中为所有患者提供护理,而没有通过症状和后续评估检测到 SARS-CoV-2 的传播。