Dermatology Clinic, Tropical Medicine Department of Federal, Clinics Hospital, University of Pernambuco, Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, 50670-901, PE, Brazil.
Medical Faculty of Recife, Centro de Ciências Médicas, Federal University of Pernambuco, Av. da Engenharia, 531-611 - Cidade Universitária, Recife, 50730-120, PE, Brazil.
Arch Dermatol Res. 2021 Sep;313(7):603-606. doi: 10.1007/s00403-020-02091-0. Epub 2020 May 14.
The disease caused by the new coronavirus (COVID-19) has many systemic manifestations affecting the upper airways, lungs, gastrointestinal tract and inducing hematological repercussions. With the evolution of the pandemic, skin lesions were observed. However, there is little information about the evolution of the lesions at this moment. The authors report a case of a patient who had more than one exposure to the coronavirus during the evolution of the disease and manifested different types of edematous lesions. The lesions started in the prodromal period and changed their presentation and localization during the evolution of COVID-19. The lesions regressed quickly with the use of corticoid cream and antihistamine. Viral skin lesions are frequent causes of exanthema. However, viral etiology is not always investigated in acute urticarial and atypical erythematous-edematous conditions. The immunological basis of acute urticaria has points in common with COVID-19, justifying the appearance of lesions. Investigation of viral etiology should always be remembered in acute urticarial and edematous conditions.
由新型冠状病毒（COVID-19）引起的疾病有许多全身表现，影响上呼吸道、肺部、胃肠道，并引起血液学反应。随着大流行的发展，观察到了皮肤损伤。然而，目前关于病变演变的信息很少。作者报告了一例患者，在疾病进展过程中曾多次接触冠状病毒，并表现出不同类型的水肿性病变。病变始于前驱期，并在 COVID-19 进展过程中改变了表现和定位。病变在使用皮质类固醇乳膏和抗组胺药后迅速消退。病毒性皮肤病变是出疹的常见原因。然而，在急性荨麻疹和非典型红斑水肿性疾病中，并非总是调查病毒病因。急性荨麻疹的免疫学基础与 COVID-19 有共同之处，这解释了病变的出现。在急性荨麻疹和水肿性疾病中，应始终记住调查病毒病因。
