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晚期肾细胞癌(RCC)的治疗管理:拉丁美洲肿瘤协作组(LACOG)和拉丁美洲肾癌协作组(LARCG)的专家小组建议。

Advanced renal cell carcinoma (RCC) management: an expert panel recommendation from the Latin American Cooperative Oncology Group (LACOG) and the Latin American Renal Cancer Group (LARCG).

机构信息

Hospital Israelita Albert Einstein, Av. Albert Einstein, 627-Morumbi, São Paulo, SP, 05652-900, Brazil.

Centro Paulista de Oncologia/Oncoclínicas, Av. Brigadeiro Faria Lima, 4300-Vila Olímpia, São Paulo, SP, 01452-000, Brazil.

出版信息

J Cancer Res Clin Oncol. 2020 Jul;146(7):1829-1845. doi: 10.1007/s00432-020-03236-4. Epub 2020 May 14.

DOI:10.1007/s00432-020-03236-4
PMID:32410064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7256074/
Abstract

PURPOSE

The outcome of RCC has improved considerably in the last few years, and the treatment options have increased. LACOG-GU and LARCG held a consensus meeting to develop guidelines to support the clinical decisions of physicians and other health professionals involved in the care of RCC patients.

METHODS

Eighty questions addressing relevant advanced RCC treatments were previously formulated by a panel of experts. The voting panel comprised 26 specialists from the LACOG-GU/LARCG. Consensus was determined as 75% agreement. For questions with less than 75% agreement, a new discussion was held, and consensus was determined by the majority of votes after the second voting session.

RESULTS

The recommendations were based on the highest level of scientific evidence or by the opinion of the RCC experts when no relevant research data were available.

CONCLUSION

This manuscript provides guidance for advanced RCC treatment according to the LACOG-GU/LARCG expert recommendations.

摘要

目的

近年来,RCC 的治疗效果有了显著提高,治疗选择也有所增加。LACOG-GU 和 LARCG 举行了一次共识会议,制定了指南,以支持参与 RCC 患者治疗的医生和其他卫生专业人员的临床决策。

方法

一个专家组预先制定了 80 个关于相关晚期 RCC 治疗的问题。投票小组成员由来自 LACOG-GU/LARCG 的 26 名专家组成。75%的一致意见确定为共识。对于未达成 75%一致意见的问题,将进行新的讨论,并在第二次投票会议后,以多数票确定共识。

结果

这些建议是基于最高水平的科学证据,或在没有相关研究数据的情况下,根据 RCC 专家的意见得出的。

结论

本文根据 LACOG-GU/LARCG 专家建议,为晚期 RCC 治疗提供了指导。

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