Department of Psychology, University "Vita-Salute San Raffaele", Milan, Italy.
Unit of Clinical Psychology and Psychotherapy, San Raffaele-Turro Hospital, Milan, Italy.
Subst Use Misuse. 2020;55(11):1746-1758. doi: 10.1080/10826084.2020.1762650. Epub 2020 May 15.
Dimensional models of personality and personality disorders (PDs) have been widely investigated among individuals with alcohol use disorders (AUD). Nevertheless, DSM-5 maladaptive personality domains showed mixed associations with AUD. Furthermore, no studies have explored the role of DSM-5 maladaptive personality domains on the comorbidity between AUD and different PDs. This study aims at investigating whether DSM-5 maladaptive personality dimensions could differentiate individuals with AUD from normative and healthy controls (HCs) subjects. The study also investigated relationships between these personality dimensions and AUD clinical features (i.e. onset, severity of concurrent substance use disorders), as well as their role in accounting for the comorbidity between AUD and PDs. This study administered the personality inventory for DSM-5 (PID-5) to 99 treatment-seeking individuals (male 68.8%; female 31.2%; age: 48.12 (14.32)) with AUD (41 AUD only; 58 AUD with PDs), comparing the participants' levels of PID-5 domains with normative data and the data from a HC sample ( 40; male 50%; female 50%; age: 48.12 (14.32)). Disinhibition and negative affectivity were relevant maladaptive personality dimensions of AUD, even when controlling for the impact of PD diagnoses. Disinhibition and negative affectivity were associated to the onset of AUD and the severity of concurrent substance use disorders. The co-occurrence of AUD and PDs is related to other two domains, namely antagonism and detachment. AUD is a complex psychopathological disorder in which both externalizing and internalizing aspects determine relevant clinical features.
人格和人格障碍（PD）的维度模型在患有酒精使用障碍（AUD）的个体中得到了广泛研究。然而，DSM-5 适应不良的人格领域与 AUD 显示出混合关联。此外，尚无研究探讨 DSM-5 适应不良的人格领域在 AUD 与不同 PD 之间共病的作用。本研究旨在调查 DSM-5 适应不良的人格维度是否可以区分 AUD 患者与正常和健康对照（HC）受试者。该研究还调查了这些人格维度与 AUD 临床特征（即发病、同时存在的物质使用障碍的严重程度）之间的关系，以及它们在解释 AUD 与 PD 之间共病的作用。本研究对 99 名寻求治疗的 AUD 患者（男性 68.8%；女性 31.2%；年龄：48.12（14.32））进行了 DSM-5 人格量表（PID-5）测试，将参与者的 PID-5 领域水平与正常数据和 HC 样本（40 名；男性 50%；女性 50%；年龄：48.12（14.32））进行了比较。即使在控制 PD 诊断的影响后，去抑制和负性情绪仍然是 AUD 的相关适应不良人格维度。去抑制和负性情绪与 AUD 的发病和同时存在的物质使用障碍的严重程度有关。AUD 和 PD 共病与其他两个领域有关，即对抗性和超脱性。AUD 是一种复杂的心理病理障碍，其中外在和内在方面决定了相关的临床特征。
