Kim Yeji, Park Minkyu, Nam Do Jin, Yang Eun Hye, Ryoo Jae-Hong
Department of Occupational and Environmental Medicine, Kyung Hee University Hospital, Seoul, Korea.
Department of Occupational and Environmental Medicine, School of Medicine, Kyung Hee University, Seoul, Korea.
Ann Occup Environ Med. 2020 Mar 5;32:e10. doi: 10.35371/aoem.2020.32.e10. eCollection 2020.
This study aimed to identify the relationship between exposure to bisphenol A (BPA) and seafood consumption using a nationally representative data of the general Korean population.
This study was conducted on 5,402 adults aged 19 years and older (2,488 men, 2,914 women) based on the second Korean National Environmental Health Survey (2012-2014). We stratified the data according to gender and analyzed urinary BPA concentrations in terms of sociodemographic characteristics, health behavior, dietary factor, and seafood consumption. In the high and low BPA exposure groups, the odds ratios (ORs) were calculated using logistic regression analysis according to the top 75th percentile concentration.
In men, large fish and tuna and other seafood categories had significantly higher ORs before and after adjustment in the group who consumed seafood more than once a week than in the group who rarely consumed seafood, with an adjusted value of 1.97 (95% confidence interval [CI]: 1.12-3.48) and 1.74 (95% CI: 1.10-2.75), respectively. In the shellfish category, the unadjusted OR was 1.61 (95% CI: 1.00-2.59), which was significantly higher in the group who consumed seafood more than once a week than in the group who rarely consumed seafood. However, the OR after adjusting for the variables was not statistically significant. In women, the frequency of seafood consumption and the concentration of urinary BPA were not significantly associated.
BPA concentration was higher in men who frequently consumed large fish and tuna, shellfish and other seafood in this study.
本研究旨在利用韩国普通人群具有全国代表性的数据，确定双酚A（BPA）暴露与海鲜消费之间的关系。
本研究基于第二次韩国国家环境卫生调查（2012 - 2014年），对5402名19岁及以上的成年人（2488名男性，2914名女性）进行。我们根据性别对数据进行分层，并从社会人口学特征、健康行为、饮食因素和海鲜消费方面分析尿中双酚A浓度。在高双酚A暴露组和低双酚A暴露组中，根据第75百分位数浓度，使用逻辑回归分析计算优势比（OR）。
在男性中，每周食用海鲜超过一次的组中，食用大鱼、金枪鱼和其他海鲜类别的调整前后OR值均显著高于很少食用海鲜的组，调整后的值分别为1.97（95%置信区间[CI]：1.12 - 3.48）和1.74（95%CI：1.10 - 2.75）。在贝类类别中，未调整的OR为1.61（95%CI：1.00 - 2.59），每周食用海鲜超过一次的组显著高于很少食用海鲜的组。然而，调整变量后的OR无统计学意义。在女性中，海鲜消费频率与尿中双酚A浓度无显著关联。
在本研究中，经常食用大鱼、金枪鱼、贝类和其他海鲜的男性双酚A浓度较高。
