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[白细胞聚集作为炎症过程的活性指标]

[Leukocyte agglomeration as an activity criterion of inflammatory processes].

作者信息

Fischer H

出版信息

Z Gesamte Inn Med. 1977 Feb 15;32(4):56-7.

PMID:324154
Abstract

The agglomeration of leucocytes serves for the proof of activation of the leucocytic system, the so-called leucergia, which among other occurs in inflammatory diseases of different genesis. On the basis of 1,000 examinations in patients with rheumatoid arthritis the sensitivity of the method was tested compared with the usual criteria of inflammation. In agroup of patients with slight activity with the agglomeration of leucocytes an inflammatory activity could be proved in 67.5% (electrophoresis 53.5%, BSR 49.2%, CrP 35.4%, leucocytosis 27.9%). The chi2-test resulted in a significant correspondence between the examinations mentioned and the agglomeration (p less than 0.001). In contrast to the usual criteria of activity the proof of leucergy is a new principle ofthe diagnostics of activity. High sensitivity and simple methodics recommend the use of the agglomeration of leucocytes in routine diagnostics.

摘要

白细胞聚集用于证明白细胞系统的激活,即所谓的白细胞反应增强,这在其他情况下会发生在不同病因的炎症性疾病中。基于对1000例类风湿性关节炎患者的检查,将该方法的敏感性与通常的炎症标准进行了比较。在一组白细胞聚集且活动轻微的患者中,67.5%的患者可证明有炎症活动(电泳53.5%,血沉49.2%,C反应蛋白35.4%,白细胞增多27.9%)。卡方检验结果表明,上述检查与白细胞聚集之间存在显著相关性(p<0.001)。与通常的活动标准不同,白细胞反应增强的证明是活动诊断的一个新原则。高敏感性和简单的方法推荐在常规诊断中使用白细胞聚集。

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