Taheri Alahyar, Sabouhi Sadegh, Farazmand Farzaneh
School of Medicine, Aja University of Medical Sciences Tehran, Iran.
School of Pharmacy, Islamic Azad University of Tehran Tehran, Iran.
Am J Clin Exp Immunol. 2020 Apr 15;9(2):6-9. eCollection 2020.
Acne vulgaris is a common complication that patients referred to dermatologist, also there are medications to manage of this such as isotretinoin, and incidence of low back pain in these patients is more than general population, so in this study we aimed to evaluate of Incidence of low back pain and sacroiliitis in military families with acne vulgaris under isotretinoin therapy.
This cross-sectional study was performed on 113 acne vulgaris patients treated with isotretinoin (at least 3 months) referred to dermatology clinic of Imam Reza Hospital of Army Medical Sciences, Tehran, Iran during 2018 to 2019. All data of patients such as dosage and duration of medication, severity of acne, incidence of low back pain, sacroiliitis and inflammatory back pain and lab data were recorded.
54% of patients had lethargy, 41.6% had myalgia and 46.9% had low back pain. Of the patients with low back pain, 54.7% had inflammatory low back pain and 45.3% had mechanical low back pain. 29 cases had inflammatory low back pain, 5 cases had sacroiliitis and one case had positive RF, the means of ESR, CRP and ANA were 19.01 ± 12.74 Mm/hr, 3.43 ± 1.27 Mg/litr and 1.31 ± 0.90, respectively.
In patients with acne vulgaris under isotretinoin therapy much attention must be given regarding to sacroiliitis and rheumatoid diseases especially when symptoms such as low back pain are present.
寻常痤疮是皮肤科门诊患者的常见并发症，治疗药物如异维A酸，且这些患者中腰痛的发生率高于普通人群，因此在本研究中，我们旨在评估接受异维A酸治疗的寻常痤疮军人家庭中腰痛和骶髂关节炎的发生率。
本横断面研究对2018年至2019年期间转诊至伊朗德黑兰陆军医学科学伊玛目礼萨医院皮肤科门诊、接受异维A酸治疗（至少3个月）的113例寻常痤疮患者进行。记录患者的所有数据，如用药剂量和疗程、痤疮严重程度、腰痛、骶髂关节炎和炎性背痛的发生率以及实验室数据。
54%的患者有嗜睡，41.6%的患者有肌痛，46.9%的患者有腰痛。在腰痛患者中，54.7%有炎性腰痛，45.3%有机械性腰痛。29例有炎性腰痛，5例有骶髂关节炎，1例类风湿因子阳性，血沉、C反应蛋白和抗核抗体的平均值分别为19.01±12.74毫米/小时、3.43±1.27毫克/升和1.31±0.90。
对于接受异维A酸治疗的寻常痤疮患者，尤其是出现腰痛等症状时，必须高度关注骶髂关节炎和类风湿疾病。
