Vanden Eynde Jean Jacques
Formerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium.
Pharmaceuticals (Basel). 2020 May 14;13(5):98. doi: 10.3390/ph13050098.
Finding efficacious and safe treatments for COVID-19 emerges as a crucial need in order to control the spread of the pandemic. Whereas plasma therapy attracts much interest, the European project Discovery focuses on the potentialities of small molecules like remdesivir, the combination of lopinavir/ritonavir, hydroxychloroquine, and chloroquine. Results recently published on the clinical evaluation of those drugs are compiled in this brief report, although complete data are still impatiently awaited.
为控制新冠疫情的传播，寻找有效且安全的新冠治疗方法成为一项迫切需求。尽管血浆疗法备受关注，但欧洲的“发现”项目聚焦于瑞德西韦、洛匹那韦/利托那韦组合、羟氯喹和氯喹等小分子药物的潜力。本简要报告汇总了近期发表的关于这些药物临床评估的结果，不过仍在急切等待完整数据。
