Cardiology Division in Geriatric Institute, Hebei General Hospital, Shijiazhuang, Hebei, China.
General Clinical Laboratory, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Nutr Metab Cardiovasc Dis. 2020 Jun 25;30(7):1057-1060. doi: 10.1016/j.numecd.2020.04.001. Epub 2020 Apr 8.
To analyze the potential mechanism of cardiovascular dysfunctions induced by Coronavirus Disease 2019 (COVID-19) and to evaluate more effective therapeutic pathways for patients with cardiovascular diseases.
COVID-19 mainly invades the lungs, causing its serious damage. Studies found that COVID-19 induced the renin-angiotensin system imbalance, inflammatory storm, hypoxemia, stress response, and so on; all contributed to hypertension and serious myocardial damage in the process of virus pathogenesis, even increasing mortality in COVID-19 patients.
In the process of management of COVID-19 infections, close attention should be paid on both lung and cardiovascular damage, especially on those with only symptoms of cardiovascular diseases. Early identification, timely and effective treatments, and maintenance of hemodynamics and electrophysiological stability are of great significance on effective treatment and long-term prognosis.
分析 2019 年冠状病毒病（COVID-19）引起的心血管功能障碍的潜在机制，并评估心血管疾病患者更有效的治疗途径。
COVID-19 主要侵犯肺部，造成严重损害。研究发现，COVID-19 引起肾素-血管紧张素系统失衡、炎症风暴、低氧血症、应激反应等，这些都有助于病毒发病过程中的高血压和严重心肌损伤，甚至增加 COVID-19 患者的死亡率。
在 COVID-19 感染的管理过程中，应密切关注肺部和心血管损伤，特别是那些仅有心血管疾病症状的患者。早期识别、及时有效的治疗以及维持血流动力学和电生理稳定性对有效治疗和长期预后具有重要意义。
