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Brugada综合征:急诊环境中非典型患者的临床表现与管理

Brugada Syndrome: Presentation and Management of the Atypical Patient in the Emergent Setting.

作者信息

Nguyen Alexander, Flores Mario, Tano Vilmogil

机构信息

Henry Ford Wyandotte Hospital, Department of Emergency Medicine, Wyandotte, Michigan.

Burrell College of Osteopathic Medicine at New Mexico State University, Department of Emergency Medicine, Las Cruces, New Mexico.

出版信息

Clin Pract Cases Emerg Med. 2020 Apr 14;4(2):251-254. doi: 10.5811/cpcem.2020.1.44675. eCollection 2020 May.

DOI:10.5811/cpcem.2020.1.44675
PMID:32426686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7220024/
Abstract

INTRODUCTION

Brugada syndrome is a genetic disorder of the heart's electrical system that increases a patient's risk of sudden cardiac death. It is a syndrome most prevalent in Southeast Asians and is found 36 times more commonly in Asians than in Hispanics.

CASE REPORT

We report and discuss a case of a 68-year-old Hispanic male who presented with clinical and electrocardiogram abnormalities consistent with Brugada syndrome.

DISCUSSION

The patient's age and ethnicity represents an atypical presentation of this rare syndrome and the lack of reported studies in the literature pertaining to these demographics reflect this.

CONCLUSION

Further studies and characterizations are necessary as manifestations continue to be unearthed. As such, Brugada Syndrome should be considered in the differential diagnosis for a myriad of patient populations.

摘要

引言

Brugada综合征是一种心脏电系统的遗传性疾病,会增加患者心源性猝死的风险。该综合征在东南亚最为普遍,在亚洲人中的发病率是西班牙裔的36倍。

病例报告

我们报告并讨论了一例68岁西班牙裔男性病例,其临床表现和心电图异常符合Brugada综合征。

讨论

患者的年龄和种族代表了这种罕见综合征的非典型表现,而文献中缺乏关于这些人口统计学特征的报道研究也反映了这一点。

结论

随着该综合征的表现不断被发现,有必要进行进一步的研究和特征描述。因此,在对众多患者群体进行鉴别诊断时应考虑Brugada综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbfd/7220024/64b1c8fa75ce/cpcem-04-251-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbfd/7220024/64b1c8fa75ce/cpcem-04-251-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbfd/7220024/64b1c8fa75ce/cpcem-04-251-g001.jpg

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Brugada Syndrome: Progress in Genetics, Risk Stratification and Management.Brugada综合征:遗传学、风险分层与管理的进展
Arrhythm Electrophysiol Rev. 2019 Mar;8(1):19-27. doi: 10.15420/aer.2018.66.2.
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Brugada-type electrocardiogram in a patient with hypothyroidism.一名甲状腺功能减退患者出现Brugada型心电图。
J Cardiol Cases. 2010 Jul 6;2(3):e147-e150. doi: 10.1016/j.jccase.2010.05.011. eCollection 2010 Dec.
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Pharmacological Therapy in Brugada Syndrome.Brugada综合征的药物治疗
Arrhythm Electrophysiol Rev. 2018 Jun;7(2):135-142. doi: 10.15420/aer.2018.21.2.
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Worldwide Prevalence of Brugada Syndrome: A Systematic Review and Meta-Analysis.全球布加综合征的患病率:一项系统评价和荟萃分析。
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Brugada Syndrome: Defining the Risk in Asymptomatic Patients.Brugada综合征:界定无症状患者的风险
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Brugada syndrome.布加综合征
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