Ustaoglu Gülbahar, Erdal Emrah, İnanır Mehmet
. Assistant Prof. Bolu Abant İzzet Baysal University, Dentistry Faculty, Department of Periodontology, Bolu, Turkey.
. Specialist Bolu Abant İzzet Baysal University, Medical Faculty, Department of Cardiology, Bolu, Turkey.
Rev Assoc Med Bras (1992). 2020 May 15;66(2):133-138. doi: 10.1590/1806-9282.66.2.133.
Periodontitis may stimulate infectious and immune response and cause the development of atherogenesis, coronary heart disease, and myocardial infarction. The aim of this study was to compare the plateletcrit (PCT) and mean platelet volume (MPV) levels derived from complete blood count (CBC) tests in patients suffering from stage 3 periodontitis with those of healthy individuals without periodontal disease.
The study included 57 patients (28 females and 29 males) with Stage 3 Periodontitis and 57 volunteering individuals (31 females and 26 males) who were periodontally healthy. The age of study participants ranged from 18 to 50 years. Their periodontal condition was investigated with probing depth (PD), clinical attachment level, bleeding on probing, and plaque index. Leukocyte (WBC) and erythrocyte count (RBC), hemoglobin (Hb) and hematocrit (HCT) levels, mean corpuscular volume (MCV) and red cell distribution width (RDW), thrombocyte count, mean platelet volume (MPV), plateletcrit (PCT ), and neutrophil and lymphocyte counts were evaluated based on the CBC test results of the study participants.
PCT, WBC, Neutrophil, and MPV values were found to be significantly higher in the periodontitis group (p<0.05). There were no significant differences in RBC counts, Hb, HCT, MCV, RDW, and platelet and lymphocyte counts between the two study groups (p>0.05).
PCT and MPV levels may be a more useful marker to determine an increased thrombotic state and inflammatory response in periodontal diseases.
牙周炎可能刺激感染和免疫反应，并导致动脉粥样硬化、冠心病和心肌梗死的发生。本研究的目的是比较重度牙周炎患者全血细胞计数（CBC）检测得出的血小板压积（PCT）和平均血小板体积（MPV）水平与无牙周疾病的健康个体的相应水平。
该研究纳入了57例重度牙周炎患者（28例女性和29例男性）以及57名牙周健康的志愿者（31例女性和26例男性）。研究参与者的年龄在18至50岁之间。通过探诊深度（PD）、临床附着水平、探诊出血和菌斑指数对他们的牙周状况进行调查。根据研究参与者的CBC检测结果评估白细胞（WBC）和红细胞计数（RBC）、血红蛋白（Hb）和血细胞比容（HCT）水平、平均红细胞体积（MCV）和红细胞分布宽度（RDW）、血小板计数、平均血小板体积（MPV）、血小板压积（PCT）以及中性粒细胞和淋巴细胞计数。
发现牙周炎组的PCT、WBC、中性粒细胞和MPV值显著更高（p<0.05）。两个研究组之间的RBC计数、Hb、HCT、MCV、RDW以及血小板和淋巴细胞计数没有显著差异（p>0.05）。
PCT和MPV水平可能是确定牙周疾病中血栓形成状态增加和炎症反应的更有用标志物。
