Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.
Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106, USA.
Curr Biol. 2020 May 18;30(10):R502-R510. doi: 10.1016/j.cub.2020.02.026.
In this primer, Cheng et al. outline what we know about the nature and control of differentiation of germline versus somatic nuclei in two groups of protozoa: the Ciliates and Foraminifera. This is shown to involve a remarkable variety of developmentally programmed phenomena such as genome editing mediated epigenetically by RNA, as well differential nuclear import.
在这篇概论中，程等人概述了我们对纤毛虫和有孔虫这两组原生动物生殖细胞核与体细胞核分化的本质和控制的了解。这涉及到许多发育编程现象，如 RNA 介导的表观遗传基因组编辑，以及核输入的差异。
