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听觉前庭临床医生对顺铂前庭毒性的经验和看法。

Audiovestibular clinician experiences and opinions about cisplatin vestibulotoxicity.

机构信息

Hearing Sciences, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.

NIHR Nottingham Biomedical Research Centre, Ropewalk House, 113 The Ropewalk, Nottingham, UK.

出版信息

Eur Arch Otorhinolaryngol. 2020 Dec;277(12):3283-3293. doi: 10.1007/s00405-020-06033-4. Epub 2020 May 19.

Abstract

PURPOSE

Vestibulotoxicity associated with cisplatin chemotherapy is known to exist, but the extent, severity, and impact is unclear from the literature. This study explored knowledge, experiences, and opinions of audiovestibular professionals about cisplatin vestibulotoxicity.

METHODS

An online survey was disseminated to clinicians working in the audiovestibular field.

RESULTS

Ninety-three respondents participated in the survey. Most professionals were aware of potential vestibulotoxicity associated with cisplatin chemotherapy. Thirty-three percent of the respondents reported that they had seen patients with cisplatin vestibulotoxicity. Forty percent of them were confident in making the diagnosis and in managing the patient in this situation. The prevalence and impact of vestibulotoxicity including practicality of the assessment should be considered when designing an effective vestibulotoxicity screening protocol.

CONCLUSION

This study provides a better understanding of cisplatin vestibulotoxicity from the perspectives of audiovestibular clinicians, which will underpin appropriate detection and management of the condition.

摘要

目的

顺铂化疗引起的前庭毒性是已知的,但文献中对此的程度、严重程度和影响尚不清楚。本研究探讨了听觉前庭专业人员对顺铂前庭毒性的知识、经验和看法。

方法

向从事听觉前庭领域工作的临床医生发放在线调查。

结果

93 名受访者参加了调查。大多数专业人员都意识到顺铂化疗可能存在前庭毒性。33%的受访者报告说他们见过顺铂前庭毒性的患者。其中 40%的人有信心做出诊断,并在这种情况下对患者进行管理。在设计有效的前庭毒性筛查方案时,应考虑前庭毒性的流行率和影响,包括评估的实用性。

结论

本研究从听觉前庭临床医生的角度更好地了解了顺铂前庭毒性,这将为该疾病的适当检测和管理提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37cc/7648001/88a514173c74/405_2020_6033_Fig1_HTML.jpg

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