垂体切除对大鼠再生肾上腺皮质有丝分裂活性的影响。
The effect of hypophysectomy on the mitotic activity of the regenerating adrenal cortex in rats.
作者信息
Nowakowska-Jankiewicz B, Lewiński A, Sewerynek E, Zieleniewski J
机构信息
Clinic of Endocrinology, Institute of Endocrinology, School of Medicine, Lódź, Poland.
出版信息
Cytobios. 1988;56(226-227):145-8.
The role of the pituitary in the regeneration of the adrenal cortex was examined. Enucleation of the left adrenal, and removal of the right adrenal were performed in hypophysectomized rats, in sham-operated control rats and in intact control rats. The mitotic activity of adrenal regenerates was evaluated on the 5th day after enucleation. A statistically significant decrease (p less than 0.001) in the mean mitotic activity rate was noted in the hypophysectomized rats, when compared with both control groups. The results obtained indicate a significant stimulating effect of the pituitary on the regeneration of the adrenal cortex in rats.
研究了垂体在肾上腺皮质再生中的作用。对垂体切除的大鼠、假手术对照大鼠和完整对照大鼠进行了左肾上腺摘除及右肾上腺切除。在摘除肾上腺后第5天评估肾上腺再生组织的有丝分裂活性。与两个对照组相比，垂体切除的大鼠平均有丝分裂活性率出现了统计学上的显著下降（p<0.001）。所得结果表明垂体对大鼠肾上腺皮质再生具有显著的刺激作用。
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