Zieleniewski J, Nowakowska-Jankiewicz B, Stepień H
Department of Experimental Endocrinology, Institute of Endocrinology, Medical Academy, Lódź, Poland.
Cytobios. 1990;61(245):85-8.
The influence of diazepam on the mitotic activity of regenerating adrenal cortex in male Wistar rats was investigated. Diazepam administration (5 mg/kg/day) was shown to inhibit the mitotic index of adrenocortical cells on the 4th and 8th day after adrenal enucleation combined with contralateral adrenalectomy. The possible mechanism of diazepam action is discussed.
研究了地西泮对雄性Wistar大鼠再生肾上腺皮质有丝分裂活性的影响。结果显示，在肾上腺去核联合对侧肾上腺切除术后第4天和第8天，给予地西泮（5毫克/千克/天）可抑制肾上腺皮质细胞的有丝分裂指数。并讨论了地西泮作用的可能机制。
