Kaba H, Saito H, Otsuka K, Seto K
Department of Physiology, Kochi Medical School, Nankoku/Japan.
Exp Clin Endocrinol. 1988 Dec;92(2):217-24. doi: 10.1055/s-0029-1210804.
The neuronal excitability of presumed A1 noradrenergic neurones in the ventrolateral medulla (VLM) which directly project to the medial preoptic/anterior hypothalamic area was analysed in pro-oestrous and metoestrous female rats under urethane anaesthesia. No significant difference was detected between the two groups for the antidromic activation threshold, absolute refractory period, frequency of successful antidromic propagation into the somatodendritic membrane, duration of post-stimulus inhibition, or spontaneous firing rate of these neurones. These results do not support the idea that the neuronal somata of A1 noradrenergic neurones in the VLM show a pro-oestrous increase in excitability during the oestrous cycle, although limitations of the methodology employed do not completely rule out this possibility.
在乌拉坦麻醉下，对动情前期和动情后期的雌性大鼠中，假定直接投射到内侧视前区/下丘脑前区的腹外侧延髓（VLM）中A1去甲肾上腺素能神经元的神经元兴奋性进行了分析。在两组之间，这些神经元的逆向激活阈值、绝对不应期、向树突-胞体膜成功逆向传播的频率、刺激后抑制的持续时间或自发放电率均未检测到显著差异。这些结果不支持VLM中A1去甲肾上腺素能神经元的神经元胞体在发情周期中兴奋性在动情前期增加的观点，尽管所采用方法的局限性并不能完全排除这种可能性。
