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基于生物力学有限元模型的常规激光屈光手术对波前像差的理论分析。

Theoretical Analysis of Wave-Front Aberrations Induced from Conventional Laser Refractive Surgery in a Biomechanical Finite Element Model.

机构信息

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出版信息

Invest Ophthalmol Vis Sci. 2020 May 11;61(5):34. doi: 10.1167/iovs.61.5.34.

Abstract

PURPOSE

To examine the biomechanical effects-induced wave-front aberrations after conventional laser refractive surgery.

METHODS

A finite element model of the human eye was established to simulate conventional laser refractive surgery with corrected refraction from -1 to -15 diopters (D). The deformation of the anterior and posterior corneal surfaces was obtained under the intraocular pressure (IOP). Then, the surface displacement was converted to wave-front aberrations.

RESULTS

Following conventional refractive surgery, significant deformation of the anterior and posterior corneal surfaces occurred because of the corneal biomechanical effects, resulting in increased residual wave-front aberrations. Deformation of the anterior surface resulted in a hyperopic shift, which was significantly increased with the increasing refractive correction. The residual high-order aberrations consisted of spherical aberration, vertical coma, and y-trefoil. Spherical aberration was significantly positively correlated to enhanced refraction correction. The effect of posterior corneal surface on induced wave-front aberration was less than the anterior corneal surface. The IOP slightly affects the postoperative defocus, coma, and spherical aberration. When treatment decentration occurred during the procedure, the hyperopic shift decreased as the eccentricity increased. Treatment decentration had a significant impact on the spherical aberration and the coma. In addition, the ocular tissue elasticity played a key role in hyperopic shift, whereas it had little effect on the other aberrations.

CONCLUSIONS

Among the many factors that affect high-order aberrations after conventional laser refractive surgery, the alterations in corneal morphology caused by biomechanical effects must be considered, as they can lead to an increase in postoperative residual wave-front aberrations.

摘要

目的

研究常规激光屈光手术后生物力学效应引起的波前像差。

方法

建立人眼的有限元模型,模拟矫正屈光度从-1 至-15 屈光度(D)的常规激光屈光手术。在眼内压(IOP)下获得前、后角膜表面的变形。然后,将表面位移转换为波前像差。

结果

常规屈光手术后,由于角膜生物力学效应,前、后角膜表面发生明显变形,导致残余波前像差增加。前表面的变形导致远视漂移,随着屈光矫正的增加而显著增加。残余高阶像差包括球差、垂直彗差和 y 三叶差。球差与增强的屈光矫正显著正相关。后角膜表面对诱导的波前像差的影响小于前角膜表面。IOP 对术后离焦、彗差和球差的影响较小。在手术过程中发生治疗偏心时,随着偏心度的增加,远视漂移减小。治疗偏心对球差和彗差有显著影响。此外,眼组织弹性在远视漂移中起关键作用,而对其他像差影响较小。

结论

在影响常规激光屈光手术后高阶像差的诸多因素中,必须考虑生物力学效应引起的角膜形态变化,因为这可能导致术后残余波前像差增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57b9/7405709/df6db6b1823a/iovs-61-5-34-f001.jpg

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