Division of Trauma, Surgical Critical Care, Burns, and Acute Care Surgery, University of California-San Diego, San Diego, California, USA.
Surg Infect (Larchmt). 2020 Sep;21(7):579-585. doi: 10.1089/sur.2020.145. Epub 2020 May 20.
The threat of antimicrobial resistance continues to grow worldwide, exacerbated by poor antibiotic stewardship practices, limited development of new antimicrobial agents, and increasing globalization. This review covers previously published studies examining how human movement contributes to the global spread of antimicrobial resistance, including between low- and middle-income and high-income countries. The emergence of resistance in one country or part of the world can become a worldwide event quickly. Human movement, including travel, medical tourism, military service, and migration, results in the globalization of resistant bacterial strains. Increased surveillance, whole-genome sequencing, focused infection control, and effective stewardship practices are needed to maintain the efficacy of antibiotics.
抗菌药物耐药性的威胁在全球范围内持续增长，这主要是由于抗生素管理不善、新抗菌药物研发受限以及全球化加剧等因素所致。本综述涵盖了先前发表的研究，这些研究探讨了人类活动如何促进抗菌药物耐药性的全球传播，包括在低收入和中等收入国家与高收入国家之间的传播。一个国家或地区的耐药性的出现可能很快成为全球性事件。人类活动，包括旅行、医疗旅游、兵役和移民，导致了耐药菌株的全球化。需要加强监测、全基因组测序、有针对性的感染控制和有效的管理措施，以维持抗生素的疗效。
