Agrawal Poonam, Chopra Deepti, Gupta Mrinal
Department of Biochemistry, Dr BSA Medical College and Hospital, New Delhi, India.
Department of Pharmacology, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh, India.
Indian J Occup Environ Med. 2020 Jan-Apr;24(1):33-35. doi: 10.4103/ijoem.IJOEM_61_19. Epub 2020 Mar 18.
Organic solvents widely used in paint manufacturing, painting, and shoemaking industries may be associated with hepatotoxicity. We present a case report of a patient with prolonged occupational exposure to organic solvents who developed transient hepatitis. Monitoring contact to these chemicals and early identification of biological markers of occupational exposure should be done. More epidemiological studies on the effects of solvents on the liver should be performed so as to help the policy makers to formulate appropriate measures to prevent detrimental effects of exposure of such chemicals. Additionally, early reporting of such cases of occupational hazards will be helpful in further understanding the incidence and possible mechanisms.
广泛应用于油漆制造、涂装和制鞋行业的有机溶剂可能与肝毒性有关。我们报告一例长期职业接触有机溶剂后发生短暂性肝炎的患者。应监测与这些化学物质的接触情况,并尽早识别职业接触的生物标志物。应开展更多关于溶剂对肝脏影响的流行病学研究,以帮助政策制定者制定适当措施,防止此类化学物质暴露产生有害影响。此外,尽早报告此类职业危害病例将有助于进一步了解其发病率和可能的机制。