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机构养老老年人的光照疗法与昼夜节律

Bright Light Therapy and Circadian Cycles in Institutionalized Elders.

作者信息

Rubiño José A, Gamundí Antoni, Akaarir Mourad, Canellas Francesca, Rial Rubén, Nicolau M Cristina

机构信息

Laboratori de Neurofisiologia del Son i Ritmes Biològics, Institut d'Investigació Sanitária Illes Balears (IDISBA), Universitat Illes Balears (UIB), Palma de Mallorca, Spain.

Institut d'Investigació Sanitaria Illes Balears (IDISBA), Hospital Universitari Son Espases (HUSE), Palma de Mallorca, Spain.

出版信息

Front Neurosci. 2020 May 6;14:359. doi: 10.3389/fnins.2020.00359. eCollection 2020.

Abstract

BACKGROUND

Bright light therapy has been found to be an efficient method to improve the main parameters of circadian rhythms. However, institutionalized elders may suffer reduced exposure to diurnal light, which may impair their circadian rhythms, cognitive performance, and general health status.

OBJECTIVES

To analyze the effects of 5 days of morning exposure for 90 min to bright light therapy (BLT) applied to institutionalized elderly subjects with mild/moderate cognitive impairment.

SUBJECTS

Thirty-seven institutionalized subjects of both sexes, aged 70-93 years.

METHODS

The study lasted three consecutive weeks. During the second week the subjects were submitted to BLT (7000-10,000 lux at eye level) on a daily basis. Cognition, attention, and sleep quality were evaluated at the beginning of the first and third week. Circadian variables were recorded continuously throughout the 3 weeks. Non-invasive holders and validated tests were used to analyze the variables studied.

RESULTS

After BLT we have found significant improvements in general cognitive capabilities, sleep quality and in the main parameters of the subject's circadian rhythms. The results show that merely 90 min of BLT for five days seems to achieve a significant improvement in a constellation of circadian, sleep, health, and cognitive factors.

CONCLUSION

Bright light therapy is an affordable, effective, fast-acting therapy for age-related disturbances, with many advantages over pharmacological alternatives. We hypothesize these effects were the result of activating the residual activity of their presumably weakened circadian system.

摘要

背景

强光疗法已被发现是改善昼夜节律主要参数的有效方法。然而,住在养老院的老年人可能白天接受光照的时间减少,这可能会损害他们的昼夜节律、认知能力和总体健康状况。

目的

分析对患有轻度/中度认知障碍的住在养老院的老年受试者进行为期5天、每天90分钟的早晨强光疗法(BLT)的效果。

受试者

37名年龄在70 - 93岁之间的住在养老院的男女受试者。

方法

研究持续三周。在第二周,受试者每天接受BLT(眼睛水平处7000 - 10000勒克斯)。在第一周和第三周开始时评估认知、注意力和睡眠质量。在整个3周内连续记录昼夜节律变量。使用非侵入性仪器和经过验证的测试来分析所研究的变量。

结果

接受BLT后,我们发现总体认知能力、睡眠质量以及受试者昼夜节律的主要参数有显著改善。结果表明,仅仅5天每天90分钟的BLT似乎就能在昼夜节律、睡眠、健康和认知等一系列因素上取得显著改善。

结论

强光疗法是一种针对与年龄相关的功能紊乱的经济实惠、有效且起效快的疗法,与药物替代疗法相比有许多优势。我们推测这些效果是激活了他们可能已减弱的昼夜节律系统的残余活性的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fa1/7218138/de4e7c031d7a/fnins-14-00359-g001.jpg

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