Kreibich Maximilian, Rylski Bartosz, Beyersdorf Friedhelm, Siepe Matthias, Czerny Martin
Department of Cardiovascular Surgery, Heart Centre Freiburg University, Freiburg, Germany.
Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Asian Cardiovasc Thorac Ann. 2021 Sep;29(7):697-700. doi: 10.1177/0218492320929211. Epub 2020 May 21.
The endovascular treatment of pathologies of the ascending aorta has not been incorporated into routine clinical practice. The aim of this article is to provide an overview of the endovascular treatment of pathologies of the ascending aorta, particularly type A aortic dissection. A thorough analysis and discussion of anatomical, physiological, clinical and technical challenges, and obstacles is performed. Conventional straight stent-grafts alone are not capable of fixing the entire complex underlying problem in the vast majority of patients with acute type A aortic dissection. An endovascular valve-carrying conduit consisting of a proximal transcatheter aortic valve connected to a covered stent-graft would be able to close a primary entry tear in the ascending aorta, ensure coronary perfusion, initiate true lumen expansion, treat malperfusion, treat aortic regurgitation, drain any pericardial effusion through a transapical approach, and possibly stabilize the distal aorta. Two thirds of all patients with acute aortic dissection are potential candidates for endovascular treatment, and the concept may help to significantly improve survival in patients with acute aortic dissection.
升主动脉病变的血管内治疗尚未纳入常规临床实践。本文旨在概述升主动脉病变,特别是A型主动脉夹层的血管内治疗。对解剖学、生理学、临床和技术方面的挑战及障碍进行了全面分析和讨论。在绝大多数急性A型主动脉夹层患者中,单纯传统的直管型覆膜支架不能解决整个复杂的潜在问题。一种由近端经导管主动脉瓣膜连接到覆膜支架组成的带瓣膜血管内导管,能够闭合升主动脉的原发破口,确保冠状动脉灌注,启动真腔扩张,治疗灌注不良,治疗主动脉瓣反流,通过经心尖途径引流任何心包积液,并可能稳定远端主动脉。所有急性主动脉夹层患者中有三分之二是血管内治疗的潜在候选者,这一概念可能有助于显著提高急性主动脉夹层患者的生存率。