In-vitro assessment of lomefloxacin (SC-47111)--a new quinolone derivative.
作者信息
Finch R, Martin J, Pilkington R
机构信息
Department of Microbial Diseases, City Hospital, Nottingham, UK.
出版信息
J Antimicrob Chemother. 1988 Dec;22(6):881-4. doi: 10.1093/jac/22.6.881.
PMID:3243735
Abstract
The activity of lomefloxacin (SC-47111) was studied in vitro against 500 clinical isolates. Comparison was made with enoxacin and ciprofloxacin. Lomefloxacin was comparable in activity to enoxacin, but less active than ciprofloxacin. Most Gram-negative bacilli were susceptible, including several multi-resistant strains. Pseudomonas aeruginosa showed variable susceptibility. Streptococci, including Streptococcus pneumoniae, were generally the least susceptible organisms.
摘要
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