细菌分离株对洛美沙星的药敏模式。
Susceptibility pattern of bacterial isolates to lomefloxacin.
作者信息
Lalitha M K, Nisha A K, Bhattacharya S S, Ramamoorthy U, Lal H M
机构信息
Department of Microbiology, Christian Medical College Hospital, Vellore, India.
出版信息
Indian J Med Res. 1990 May;91:182-4.
The in vitro susceptibility pattern with respect to lomefloxacin was determined in case of 1009 bacterial isolates from clinical specimens with varying susceptibility to commonly used antimicrobial agents. The MIC50 and MIC90 values of lomefloxacin for the Gram negative bacilli showed susceptibility value ranging between 0.12 to 4.0 micrograms/ml, while 90 per cent of the streptococci tested were inhibited only at 16 micrograms/ml. Lomefloxacin was comparable in activity to enoxacin and ciprofloxacin but it was more active than norfloxacin and nalidixic acid.
针对1009株来自临床标本的细菌分离株，测定了它们对洛美沙星的体外药敏模式，这些分离株对常用抗菌药物的敏感性各不相同。洛美沙星对革兰氏阴性杆菌的MIC50和MIC90值显示，药敏值在0.12至4.0微克/毫升之间，而所检测的链球菌中，90%仅在16微克/毫升时才受到抑制。洛美沙星的活性与依诺沙星和环丙沙星相当，但比诺氟沙星和萘啶酸更具活性。
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