Feher M D, Rampling M W, Sever P S, Elkeles R S
Department of Clinical Pharmacology, St. Mary's Hospital Medical School, London, UK.
J Hum Hypertens. 1988 Aug;2(2):117-22.
Fibrinogen and blood viscosity were measured in 72 stable non-insulin dependent diabetic subjects, 31 without hypertension, and 41 who had treated hypertension. The hypertensive group had higher plasma fibrinogen levels and blood viscosity. As both these rheological variables have been associated with micro- and macro-vascular disease, these findings may provide a possible explanation for the mechanism of the increased vascular disease seen in hypertensive compared with normotensive diabetic subjects.
对72名病情稳定的非胰岛素依赖型糖尿病患者进行了纤维蛋白原和血液粘度的测量，其中31人无高血压，41人患有经治疗的高血压。高血压组的血浆纤维蛋白原水平和血液粘度更高。由于这两个流变学变量都与微血管和大血管疾病有关，这些发现可能为高血压糖尿病患者与血压正常的糖尿病患者相比血管疾病增加的机制提供一种可能的解释。
