Memeh C U
Department of Physiology, School of Medicine, College of Medical Sciences, University of Benin, Nigeria.
Horm Metab Res. 1993 Jan;25(1):21-3. doi: 10.1055/s-2007-1002038.
Plasma and serum viscosity and associated protein titres were determined in short- and long term types 1 and 2 diabetic Africans. The viscosity of plasma and serum, fibrinogen, total serum protein and albumin concentrations of both short- and longterm type 1 diabetics were significantly greater than those of the nondiabetic controls, although no significant differences in these parameters were recorded between the two groups of type 1 diabetics. There were no significant differences between short term type 2 diabetics and the controls in the parameters examined except albumin which is significantly higher in the former. However, plasma and serum viscosity, fibrinogen, total serum protein protein and albumin of longterm type 2 diabetics were significantly elevated above those of the control group. These results show that there is an earlier presentation of cardiovascular risk factors in type 1 than in type 2 diabetic Africans.
对短期和长期的1型及2型糖尿病非洲患者测定了血浆和血清粘度以及相关蛋白滴度。短期和长期1型糖尿病患者的血浆和血清粘度、纤维蛋白原、总血清蛋白和白蛋白浓度均显著高于非糖尿病对照组,不过两组1型糖尿病患者在这些参数上并无显著差异。除白蛋白(短期2型糖尿病患者的白蛋白显著更高)外,所检测参数在短期2型糖尿病患者与对照组之间并无显著差异。然而,长期2型糖尿病患者的血浆和血清粘度、纤维蛋白原、总血清蛋白和白蛋白均显著高于对照组。这些结果表明,1型糖尿病非洲患者比2型糖尿病非洲患者更早出现心血管危险因素。