College of Life Sciences, Hebei Agricultural University, Baoding, China.
Research Center of Chinese Jujube, Hebei Agricultural University, Baoding, China.
Microbes Infect. 2020 Jul-Aug;22(6-7):272-277. doi: 10.1016/j.micinf.2020.05.011. Epub 2020 May 20.
Hantavirus (HV), a pathogen of animal infectious diseases that poses a threat to humans, has attracted extensive attention. Clinically, HV can cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), between which HFRS is mostly in Eurasia, and HPS is mostly in the Americas. This paper reviews the research progress of small-molecule inhibitors of HV.
汉坦病毒(HV)是一种对人类具有威胁的动物传染病病原体,引起了广泛关注。临床上,HV 可引起肾综合征出血热(HFRS)和汉坦病毒肺综合征(HPS),其中 HFRS 主要在欧亚大陆,HPS 主要在美洲。本文综述了 HV 小分子抑制剂的研究进展。