自闭症谱系障碍（ASD）幼儿治疗效果评估的最新进展。
Recent Developments in Treatment Outcome Measures for Young Children With Autism Spectrum Disorder (ASD).
机构信息
University of North Carolina, Carolina Institute for Developmental Disabilities, Chapel Hill, NC.
Center for Autism and the Developing Brain, Weill Cornell Medical College, New York-Presbyterian Hospital, White Plains, NY.
出版信息
Semin Pediatr Neurol. 2020 Jul;34:100806. doi: 10.1016/j.spen.2020.100806. Epub 2020 Mar 6.
Abstract
Significant advancements have been made in early intervention programs for children with Autism spectrum disorder (ASD). However, measuring treatment response for children with ASD is difficult due to the heterogeneity of changes in symptoms, which can be subtle, especially over a short period of time. Here we outline the challenge of evaluating treatment response with currently available measures as well as newly developed or refined measures that may be useful in clinical trials for young children with ASD. Continued development of treatment outcome measures will help the field identify and compare efficacious interventions and tailor treatments for children with ASD.
摘要
在自闭症谱系障碍（ASD）儿童的早期干预方案方面已经取得了重大进展。然而，由于症状变化的异质性，评估 ASD 儿童的治疗反应具有挑战性，特别是在短时间内。在这里，我们概述了使用当前可用的测量方法以及新开发或改进的测量方法评估治疗反应的挑战，这些方法可能对 ASD 幼儿的临床试验有用。治疗结果测量方法的持续发展将有助于该领域确定和比较有效的干预措施，并为 ASD 儿童量身定制治疗方法。
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