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术前内镜活检诊断为侵犯整个主胰管的胰腺神经内分泌肿瘤

Pancreatic Neuroendocrine Neoplasm Invading the Entire Main Pancreatic Duct Diagnosed by a Preoperative Endoscopic Biopsy.

作者信息

Kimura Tomoya, Sugimoto Mitsuru, Takagi Tadayuki, Suzuki Rei, Konno Naoki, Asama Hiroyuki, Sato Yuki, Irie Hiroki, Nakamura Jun, Takasumi Mika, Hashimoto Minami, Kato Tsunetaka, Kofunato Yasuhide, Kimura Takashi, Yamada Shoki, Hashimoto Yuko, Marubashi Shigeru, Hikichi Takuto, Ohira Hiromasa

机构信息

Department of Gastroenterology, School of Medicine, Fukushima Medical University, Japan.

Department of Endoscopy, Fukushima Medical University Hospital, Japan.

出版信息

Intern Med. 2020 Aug 15;59(16):1991-1996. doi: 10.2169/internalmedicine.4546-20. Epub 2020 May 23.

DOI:10.2169/internalmedicine.4546-20
PMID:32448838
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7492121/
Abstract

A 78-year-old man was referred to our hospital for a detailed examination of a pancreatic tumor that filled the main pancreatic duct (MPD). The histological diagnosis of the endoscopic biopsy specimen was neuroendocrine tumor (NET) G3. The patient subsequently underwent total pancreatectomy. The histological diagnosis of the surgical specimen was also NET G3. This is the first report of a NET that occupied the MPD and was diagnosed by a preoperative endoscopic biopsy through the papilla of Vater. This case is a good example of a histopathological diagnostic method for pancreatic tumors invading the entire MPD.

摘要

一名78岁男性因对占据主胰管(MPD)的胰腺肿瘤进行详细检查而转诊至我院。内镜活检标本的组织学诊断为神经内分泌肿瘤(NET)G3。该患者随后接受了全胰切除术。手术标本的组织学诊断同样为NET G3。这是首例通过术前经十二指肠乳头内镜活检诊断出占据主胰管的神经内分泌肿瘤的报告。该病例是胰腺肿瘤侵犯整个主胰管的组织病理学诊断方法的一个良好范例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/61ef4e6ba384/1349-7235-59-1991-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/7933d1299892/1349-7235-59-1991-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/b628e08f9690/1349-7235-59-1991-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/bcc54f0463c0/1349-7235-59-1991-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/61ef4e6ba384/1349-7235-59-1991-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/7933d1299892/1349-7235-59-1991-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/b628e08f9690/1349-7235-59-1991-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/bcc54f0463c0/1349-7235-59-1991-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/203e/7492121/61ef4e6ba384/1349-7235-59-1991-g004.jpg

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本文引用的文献

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World J Clin Oncol. 2017 Jun 10;8(3):293-299. doi: 10.5306/wjco.v8.i3.293.
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Differentiation of pancreatic neuroendocrine carcinoma from pancreatic ductal adenocarcinoma using magnetic resonance imaging: The value of contrast-enhanced and diffusion weighted imaging.利用磁共振成像鉴别胰腺神经内分泌癌与胰腺导管腺癌:对比增强成像和扩散加权成像的价值
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Is the combination of MR and CT findings useful in determining the tumor grade of pancreatic neuroendocrine tumors?
磁共振成像(MR)和计算机断层扫描(CT)检查结果的组合对于确定胰腺神经内分泌肿瘤的肿瘤分级是否有用?
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Pancreatic Duct Involvement in Well-Differentiated Neuroendocrine Tumors is an Independent Poor Prognostic Factor.胰腺导管受累在高分化神经内分泌肿瘤中是一个独立的不良预后因素。
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Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors: A Retrospective Nationwide Multicenter Study in South Korea.美国癌症联合委员会和欧洲神经内分泌肿瘤分期分类对胰腺神经内分泌肿瘤的预后有效性:韩国一项全国性多中心回顾性研究
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