Ehnholm C, Heaf D J, Kaijser L, Kinnunen P K, Carlson L A
Atherosclerosis. 1977 May;27(1):35-9. doi: 10.1016/0021-9150(77)90021-1.
Low doses of heparin were injected into the brachial artery of three volunteers. The lipase activities in the deep vein of the same forearm, draining mainly muscle tissue, and in the artery were monitored over a 10-min period. Lipase activity, rapidly released by heparin in the deep vein, was immunologically similar to lipoprotein lipase (E.C. 3.1.1.3), i.e. (1) it did not react with antiserum against human post-heparin plasma hepatic lipase and (2) it was inhibited by an antiserum against bovine milk lipoprotein lipase, which cross reacts with human post-heparin plasma lipoprotein lipase. The evidence that human muscle contains lipoprotein lipase is discussed.
向三名志愿者的肱动脉注射低剂量肝素。在10分钟内监测同一前臂主要引流肌肉组织的深静脉和动脉中的脂肪酶活性。肝素在深静脉中迅速释放的脂肪酶活性在免疫学上与脂蛋白脂肪酶（E.C. 3.1.1.3）相似，即（1）它不与抗人肝素后血浆肝脂肪酶的抗血清发生反应，（2）它被抗牛乳脂蛋白脂肪酶的抗血清抑制，该抗血清与人肝素后血浆脂蛋白脂肪酶发生交叉反应。文中讨论了人类肌肉中含有脂蛋白脂肪酶的证据。
