Department of Chemistry and Pharmacy, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.
Mediterranean Institute for Agriculture, Environment and Development, Department of Chemistry and Pharmacy, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.
Z Naturforsch C J Biosci. 2020 Jul 28;75(7-8):233-245. doi: 10.1515/znc-2020-0044.
Spontaneous lavender growing in uncultivated fields in Portugal have been used in traditional medicine for internal and external uses. The essential oils (EOs) of Lavandula stoechas subsp. luisieri are characterized by the presence of trans-α-necrodyl acetate and trans-necrodol. These EOs are able to prevent the generation and deposition of neurotoxic β-amyloid peptide in Alzheimer's disease. The EOs also present antibacterial, anti-fungal, anti-Leishmania, antioxidant, anti-inflammatory and antifeedant effects. In the case of hydrodistillation, the predominant compound of Lavandula viridis EO was 1,8-cineole, nevertheless in the case of supercritical fluid extraction, the main constituent was camphor. In in vitro shoots EOs, 1,8-cineole and α-pinene were the most important compounds. The EOs presented anti-fungal activity particularly against Cryptococcus neoformans and dermatophytes. The antioxidant and anti-protozoal activities of L. viridis EOs were lower than L. stoechas subsp. luisieri EOs, with hydrodistillation being the best method for obtaining samples with higher antioxidant and anti-acetylcholinesterase activities. The presence of fenchone, 1,8-cineole and camphor was a common trace of the Lavandula pedunculata subsp. pedunculata EOs and in in vitro axillary shoots EOs. Lavandula pedunculata subsp. lusitanica EOs were predominantly constituted of fenchone and camphor. The antioxidant activity of L. pedunculata subsp. lusitanica EOs was poorer than other Lavandula EOs from Portugal.
自发生长在葡萄牙未开垦田地中的薰衣草已被用于传统医学的内用和外用。薰衣草亚种。louisieri 的精油 (EO) 的特点是存在反式-α-新二乙酰和反式新二醇。这些 EO 能够预防阿尔茨海默病中神经毒性 β-淀粉样肽的产生和沉积。EO 还具有抗菌、抗真菌、抗利什曼原虫、抗氧化、抗炎和抗食作用。在水蒸馏的情况下，薰衣草精油的主要化合物是 1,8-桉树脑，然而在超临界流体萃取的情况下，主要成分是樟脑。在体外芽 EO 中，1,8-桉树脑和α-蒎烯是最重要的化合物。EO 对新型隐球菌和皮肤真菌具有抗真菌活性。薰衣草精油的抗氧化和抗原生动物活性低于薰衣草亚种。louisieri EO，水蒸馏是获得具有更高抗氧化和抗乙酰胆碱酯酶活性的样品的最佳方法。在薰衣草 pedunculata subsp. pedunculata EO 中，fenchone、1,8-桉树脑和樟脑是常见的痕量物质，在体外腋芽 EO 中也是如此。薰衣草 pedunculata subsp. lusitanica EO 主要由 fenchone 和樟脑组成。薰衣草 pedunculata subsp. lusitanica EO 的抗氧化活性比葡萄牙其他薰衣草 EO 差。
