Picheta Natalia, Piekarz Julia, Daniłowska Karolina, Mazur Karol, Piecewicz-Szczęsna Halina, Smoleń Agata
Chair and Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, Lublin, Poland.
Front Psychiatry. 2024 Dec 9;15:1509109. doi: 10.3389/fpsyt.2024.1509109. eCollection 2024.
Depression is a complex mental disease whose incidence increases every year; 300 million people worldwide currently suffer from it. Women are more likely to suffer from depression, twice the rate as men. It is one of the few illnesses that can lead to suicide, which makes it very dangerous - currently, 700,000 people die from suicide and it is the 4th most common cause of death in people aged 15-29. The treatment strategies for depression is a big challenge for physicians, pharmacists, scientists and classic remedies cause many side effects. Therefore, natural phytotherapy with herbs can prove to be a good solution. Phytotherapy is a popular treatment method used for centuries in Chinese medicine or Ayurveda.
The study conducted a comprehensive database search PubMed, ClinicalKey and MedNar covered the years 2015 - 2024 to provide the most up-to-date data. 13 randomized controlled trials and 1 meta - analysis were included in the systematic review.
Many plants show anti-inflammatory, antioxidant and cognitive enhancing effects, which are particularly important in depression. In the treatment of depression, plants such as , and . have proven to be effective. They show good effectiveness in human studies and alleviate the symptoms of depression. Herbal products can support classical pharmacotherapy, but this requires further research. Non-commercial clinical trials in the future should provide answers to research questions: at what stage of treatment of patients with MDD will the use of phytochemicals be most appropriate in terms of therapy efficacy and safety for the patient.
, and . in modern medicine can help improve the well-being of patients with depression. The use of herbs as an intervention was associated with a decrease in the concentration of proinflammatory cytokines and an overall improvement in the mood of patients. Further research should be undertaken into combining both therapies in order to improve patients' quality of life and reduce treatment costs.
抑郁症是一种复杂的精神疾病，其发病率逐年上升；目前全球有3亿人患有此病。女性更容易患抑郁症，患病率是男性的两倍。它是少数能导致自杀的疾病之一，这使其非常危险——目前，每年有70万人死于自杀，是15至29岁人群中第四大常见死因。抑郁症的治疗策略对医生、药剂师和科学家来说是一项巨大挑战，传统疗法会引发许多副作用。因此，草药自然植物疗法可能是一个不错的解决方案。植物疗法是一种在中国医学或阿育吠陀医学中已使用数百年的流行治疗方法。
该研究对PubMed、ClinicalKey和MedNar进行了全面的数据库检索，涵盖2015年至2024年，以提供最新数据。系统评价纳入了13项随机对照试验和1项荟萃分析。
许多植物具有抗炎、抗氧化和增强认知的作用，这在抑郁症治疗中尤为重要。在抑郁症治疗中，诸如[此处原文缺失植物名称]等植物已被证明有效。它们在人体研究中显示出良好疗效，可缓解抑郁症状。草药产品可辅助传统药物治疗，但这需要进一步研究。未来的非商业临床试验应回答以下研究问题：就治疗效果和患者安全性而言，在重度抑郁症患者治疗的哪个阶段使用植物化学物质最为合适。
[此处原文缺失植物名称]等植物在现代医学中有助于改善抑郁症患者身心健康。使用草药作为干预措施与促炎细胞因子浓度降低以及患者情绪整体改善相关。应进一步研究将两种疗法结合使用，以提高患者生活质量并降低治疗成本。
