Domingues Joana, Delgado Fernanda, Gonçalves José Carlos, Zuzarte Mónica, Duarte Ana Paula
Plant Biotechnology Centre of Beira Interior (CBPBI), 6001-909 Castelo Branco, Portugal.
Health Sciences Research Centre (CICS), University of Beira Interior, 6200-506 Covilhã, Portugal.
Metabolites. 2023 Feb 24;13(3):337. doi: 10.3390/metabo13030337.
Globally, climate change and wildfires are disrupting natural ecosystems, thus setting several endemic species at risk. The genus is widely present in the Mediterranean region and its species, namely, those included in the section are valuable resources of active compounds with several biological assets. Since ancient times lavenders have been used in traditional medicine and for domestic purposes. These species are melliferous, decorative, and essential oil-producing plants with a high economic interest in the pharmaceutical, flavor, fragrance, and food industries. The essential oils of section are characterized by high amounts of 1,8-cineole, camphor, fenchone, and specifically for subsp. one of the major compounds is -α-necrodyl acetate. On the other hand, the diversity of non-volatile components like phenolic compounds, such as phenolic acids and flavonoids, make these species an important source of phytochemicals with pharmacological interest. Rosmarinic, caffeic, and salvianolic B acids are the major phenolic acids, and luteolin and eriodictyol--glucuronide are the main reported flavonoids. However, the concentration of these secondary metabolites is strongly affected by the plant's phenological phase and varies in sp. from different areas of origin. Indeed, lavender extracts have shown promising antioxidant, antimicrobial, anti-inflammatory, and anticancer properties as well as several other beneficial actions with potential for commercial applications. Despite several studies on the bioactive potential of lavenders from the section , a systematized and updated review of their chemical profile is lacking. Therefore, we carried out the present review that gathers relevant information on the different types of secondary metabolites found in these species as well as their bioactive potential.
在全球范围内，气候变化和野火正在扰乱自然生态系统，从而使几种特有物种面临风险。薰衣草属在地中海地区广泛存在，其物种，即该组中的那些物种，是具有多种生物特性的活性化合物的宝贵资源。自古以来，薰衣草就被用于传统医学和家庭用途。这些物种是产蜜、装饰性和生产精油的植物，在制药、香料、香水和食品工业中具有很高的经济价值。该组薰衣草的精油以含有大量的1,8-桉叶素、樟脑、小茴香酮为特征，特别是对于subsp. ，主要化合物之一是-α-新克罗二醇乙酸酯。另一方面，酚类化合物等非挥发性成分的多样性，如酚酸和黄酮类化合物，使这些物种成为具有药理学意义的植物化学物质的重要来源。迷迭香酸、咖啡酸和丹酚酸B是主要的酚酸，木犀草素和圣草酚-葡萄糖醛酸苷是主要报道的黄酮类化合物。然而，这些次生代谢物的浓度受到植物物候期的强烈影响，并且在来自不同产地的sp.中有所不同。事实上，薰衣草提取物已显示出有前景的抗氧化、抗菌、抗炎和抗癌特性以及其他几种具有商业应用潜力的有益作用。尽管对该组薰衣草的生物活性潜力进行了多项研究，但缺乏对其化学特征的系统和更新的综述。因此，我们进行了本综述，收集了有关这些物种中发现的不同类型次生代谢物及其生物活性潜力的相关信息。
