Gardner D G
Division of Oral Pathology and Oncology, University of Colorado School of Dentistry, Denver, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 May;79(5):612-5. doi: 10.1016/s1079-2104(05)80104-0.
This article describes the acanthomatous epulis in dogs, a quite common lesion that appears to be the counterpart of human ameloblastoma. Histologically, it resembles closely the acanthomatous pattern of human ameloblastoma and, like ameloblastomas in human beings, it infiltrates cancellous bone; moreover, it has no tendency to metastasize. Veterinarians have sometimes treated the acanthomatous epulis with therapeutic irradiation, providing one example when this tumor served as an animal model for human ameloblastoma. Although this treatment has cured some animals, others have developed postirradiation malignancies.
本文描述了犬齿龈棘皮瘤，这是一种相当常见的病变，似乎是人类成釉细胞瘤的对应物。在组织学上，它与人类成釉细胞瘤的棘皮瘤模式非常相似，并且像人类的成釉细胞瘤一样，它会浸润松质骨；此外，它没有转移倾向。兽医有时会用放射治疗来治疗龈棘皮瘤，这为该肿瘤作为人类成釉细胞瘤的动物模型提供了一个例子。尽管这种治疗方法治愈了一些动物，但其他动物却出现了放疗后恶性肿瘤。
